Results 191 to 200 of about 419,002 (339)

Importance of SUMOylation Consensus Sequence of MAFK in Regulating EMT, Tumor Growth, Stemness, and Drug Resistance

open access: yesCancer Science, EarlyView.
In this study, we focused on SUMOylation, a posttranslational modification, and investigated the importance of its consensus sequence in MAFK. We demonstrated that the non‐SUMOylation mimic mutant MAFK (EA) impairs MAFK‐induced EMT, cellular migration and invasion, tumor and sphere formation, acquisition of stem‐like properties, and drug resistance ...
Thuy Linh Dang Cao   +7 more
wiley   +1 more source

Case of Laryngeal Neoplasm [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1914
openaire   +1 more source

Oral Health—Head and Neck Cancers: Addressing Confounding Through Negative Control and Quantitative Bias Analyses

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives While there are plausible biological explanations for the association between oral health and head and neck cancers (HNC), existing studies have yielded conflicting results. A key concern is that these associations are influenced by mediators, unmeasured risk factors, and biases. To address this, a negative control exposure was used
P. K. Elango   +5 more
wiley   +1 more source

Surgical Outcomes Following Neoadjuvant‐Targeted Therapy for Advanced Differentiated Thyroid Cancer—Real‐World Data

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Background Differentiated thyroid carcinoma (DTC) is typically managed surgically with favourable outcomes. However, surgery may have dire consequences when the tumour invades critical structures. Neoadjuvant therapy with tyrosine kinase inhibitors (TKIs) has emerged as a potential strategy to improve resectability and reduce morbidity in ...
Alexandra Dorman   +15 more
wiley   +1 more source

Predicting Local Recurrence in T3 Laryngeal Squamous Cell Carcinoma: An Analysis of Tumor Volume and Cartilage Invasion Prior to Radiotherapy. [PDF]

open access: yesCancer Med
Blomkvist R   +6 more
europepmc   +1 more source

Low Alanine Aminotransferase Blood Activity, a Biomarker of Sarcopenia and Frailty, is Associated With Worse Post‐Total Laryngectomy Clinical Outcomes. A Retrospective Analysis of 427 Patients

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Introduction Sarcopenia and frailty status have been shown to be associated with cancer patients' survival. Low alanine aminotransferase (ALT) blood activity was previously shown to be associated with frailty and poor clinical outcomes in cancer patients. This association was not addressed in head and neck cancer patients.
Yarden Tenenbaum Weiss   +8 more
wiley   +1 more source

Anatomical variations of the recurrent laryngeal nerve and postoperative outcomes in thyroid surgeries conducted at a teaching hospital in Ethiopia. [PDF]

open access: yesSci Rep
Wubie AG   +10 more
europepmc   +1 more source

Simultaneous Head and Neck and Lung Cancers: Implications and Therapeutic Management Timing

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Objectives This study aims to describe the characteristics of patients with simultaneous head and neck squamous cell carcinomas (HNSCCs) and lung cancer and to assess the impact of diagnosis‐to‐treatment interval (DTI) and treatment choices on outcomes. Design and Setting A bicentric retrospective observational study conducted between 2003 and
Dario Ebode   +9 more
wiley   +1 more source

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