Results 201 to 210 of about 14,436 (352)

Moderate Laryngeal Dysplasia in the Context of Classification Systems and Clinical Decision Making

open access: yesThe Laryngoscope, EarlyView.
There is still an ongoing debate about the classification of laryngeal dysplasia. In a large retrospective analysis of 392 patients, the progression of dysplasia and the risk of a de novo occurrence of invasive carcinoma were evaluated. Here especially the high rate of occurrence of invasive carcinoma in the group of moderate dysplasia with 44% is of ...
Flurin Mueller‐Diesing   +11 more
wiley   +1 more source

The Role of Tumor Budding in Early‐Stage Laryngeal Cancer Treatment Selection

open access: yesThe Laryngoscope, EarlyView.
The search for treatment choices in the treatment of early‐stage laryngeal cancer is still ongoing. In this group with high treatment rates, it is important to be able to predict the unsuccessful group in advance. Tumor budding shows promising results. The failure rate after radiotherapy is high in patients with tumor budding of 2 or more.
Mehmet Birinci   +7 more
wiley   +1 more source

HPV6‐Induced Gene Expression Signature in Recurrent Respiratory Papillomatosis

open access: yesThe Laryngoscope, EarlyView.
Using the conditional reprogramming method, we established a cell culture model of recurrent respiratory papillomatosis and analyzed gene expression. Genes related to human papillomavirus 6 expression were identified, including inflammatory genes (e.g., CTSS, CFB), oncogenic genes (e.g., CEACAM5, CEACAM6), and glycosylation‐associated genes (e.g ...
Naoyuki Matsumoto   +10 more
wiley   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury   +2 more
wiley   +1 more source

Case report: A case report on surgical management of laryngeal paraganglioma. [PDF]

open access: yesInt J Surg Case Rep
Biru MT   +4 more
europepmc   +1 more source

Advancements in Magnesium Applications, Biocompatible Implants to Nanoparticles in Medicine and Biomedical Innovations

open access: yesMetalMat, EarlyView.
Magnesium (Mg) and its alloys are identified as prospective materials for orthopedic and cardiovascular applications because of their bio‐corrosiveness and ability to stimulate tissue reparative processes. Although compared with traditional metals, Mg is biocompatible; however, it has various problems that stem from its biodegradation nature, for ...
Muhammad Mubeen   +6 more
wiley   +1 more source

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