Follicular nodules (Thy3) of the thyroid: is total thyroidectomy the best option? [PDF]
BACKGROUND: Identification of the best management strategy for nodules with Thy3 cytology presents particular problems for clinicians. This study investigates the ability of clinical, cytological and sonographic data to predict malignancy in ...
CALO', PIETRO GIORGIO+6 more
core +1 more source
RASEC: Rescaling Acquisition Strategy with Energy Constraints under SE-OU Fusion Kernel for Active Trachea Palpation and Incision Recommendation in Laryngeal Region [PDF]
A novel palpation-based incision detection strategy in the laryngeal region, potentially for robotic tracheotomy, is proposed in this letter. A tactile sensor is introduced to measure tissue hardness in the specific laryngeal region by gentle contact.
arxiv
The evolution of the epidemiological landscape of head and neck cancer in Italy: Is there evidence for an increase in the incidence of potentially HPV-related carcinomas? [PDF]
The current study aimed to investigate the incidence and survival patterns of HNSCCs arising from different anatomic sites, potentially related (the oropharynx) or unrelated (the oral cavity, the larynx/hypopharynx) to HPV, to provide clues on possible ...
Annarosa Del Mistro+9 more
core +4 more sources
Gender, Smoking History and Age Prediction from Laryngeal Images [PDF]
Flexible laryngoscopy is commonly performed by otolaryngologists to detect laryngeal diseases and to recognize potentially malignant lesions. Recently, researchers have introduced machine learning techniques to facilitate automated diagnosis using laryngeal images and achieved promising results.
arxiv
PET/CT incidental detection of second tumor in patients investigated for pancreatic neoplasms [PDF]
Positron Emission Tomography/computed tomography (PET/CT) is an imaging technique which has a role in the detection and staging malignancies (both in first diagnosis and follow-up).
Bissoli, Sergio+5 more
core +2 more sources
Mathematical models for order of mutation problem in myeloproliferative neoplasm: non-additivity and non-commutativity [PDF]
In some patients of myeloproliferative neoplasm, two genetic mutations can be found: JAK2 V617F and TET2. When one mutation is present or not, the other mutation has different effects on regulating gene expressions. Besides, when both mutations are present, the order of occurrence might make a difference.
arxiv
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Practical tips to reduce complication rate in thyroidectomy
Introduction: Thyroid cancer is the most frequent endocrine neoplasm, and its incidence has been consistently rising during the last decades. Surgical treatment is the choice, but the complications can be truly devastating. Methods: The objective of this
Claudio Cernea+11 more
doaj +1 more source
Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm [PDF]
We develop a modeling framework for cancer progression that distinguishes the order of two possible mutations. Recent observations and information on myeloproliferative neoplasms are analyzed within our framework. In some patients with myeloproliferative neoplasms, two genetic mutations can be found, JAK2 V617F and TET2.
arxiv