Single‐Cell Transcriptomics Identifies Novel Prognostic Signatures in HNSCC Immunotherapy Response
This study demonstrates the value of combining single‐cell and bulk RNA sequencing approaches to understand HNSCC tumor biology and treatment response. The developed prognostic model and identified immune signatures provide a foundation for improving patient stratification and treatment selection.
Kankui Wu+8 more
wiley +1 more source
First Report of the Coexistence of Langerhans Cell Histiocytosis and Epithelioid Hemangioma of the Larynx. [PDF]
Meral SC+4 more
europepmc +1 more source
Head and Neck Cancer Immunotherapy: Overcoming Limitations and Enhancing Efficacy
ICI‐included therapies are standard for R/M HNSCC patients. In particular, neoadjuvant ICI therapy shows promising clinical results even in nontreated resectable HNSCC patients. In addition, cancer vaccine, immune cell‐based therapy, immunomodulation therapy, and TME targeting therapy may combine with ICI.
Hirofumi Shibata+8 more
wiley +1 more source
Trends, levels, and projections of Head and Neck Cancer in China between 2000 and 2021: Findings from the Global Burden of Disease 2021. [PDF]
Wu M, Chen H, Zhang W, Feng X, Zhang S.
europepmc +1 more source
Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan+14 more
wiley +1 more source
G2 neuroendocrine tumors of the larynx: A case report. [PDF]
Yang T, Xiao L, Ren H.
europepmc +1 more source
ABSTRACT Objectives This study aimed to investigate implant outcomes in patients with head and neck cancer undergoing radiotherapy or chemotherapy by incorporating the latest research findings. Methods The present review was conducted to update the focused question: What is the survival rate of implants placed in patients with head and neck cancer ...
Shengchi Fan+5 more
wiley +1 more source
Analysis of the mortality trends of laryngeal cancer attributable to smoking worldwide from 1990 to 2021 and projections up to 2036. [PDF]
Yang J, Chen XS, Lu Y.
europepmc +1 more source
Causal links between iron status, mitochondrial function, and laryngeal and hypopharyngeal cancers: a Mendelian study. [PDF]
Zhao J+6 more
europepmc +1 more source