Results 1 to 10 of about 105,854 (165)

Intrinsic velocity differences between larynx raising and larynx lowering.

PLoS ONE, 2023
In this study, 23 subjects produced cyclic transitions between rounded vowels and unrounded vowels as in /o-i-o-i-o-…/ at two specific speaking rates. Rounded vowels are typically produced with a lower larynx position than unrounded vowels. This contrast
Christian Kleiner, Patrick Häsner, Peter Birkholz   +2 more
doaj   +2 more sources

The Effect of Tobacco Smoke N-Nitrosamines, NNK and NDEA, and Nicotine, on DNA Mismatch Repair Mechanism and miRNA Markers, in Hypopharyngeal Squamous Cell Carcinoma: An In Vivo Model and Clinical Evidence

Current Oncology, 2022
Deregulation of the DNA mismatch repair (MMR) mechanism has been linked to poor prognosis of upper aerodigestive tract cancers. Our recent in vitro data have provided evidence of crosstalk between deregulated miRNAs and MMR genes, caused by tobacco smoke
Sotirios G. Doukas, Dimitra P. Vageli, Panagiotis G. Doukas, Dragana Nikitovic, Aristidis Tsatsakis, Benjamin L. Judson   +5 more
doaj   +1 more source

Trend and projection of larynx cancer incidence and mortality in China from 1990 to 2044: A Bayesian age–period–cohort modeling study

Cancer Medicine, 2023
Background Larynx cancer is one of the most common cancers in head and neck, and imposes heavy burden on individual and societies. A comprehensive understanding of the burden of larynx cancer is necessary to improve prevention and control strategies ...
Enlin Ye, Jiasheng Huang, Jia Wang, Yumei Zhao, Dongdong Niu, Jie Liu, Xueying Huang, Suru Yue, Xuefei Hou, Jiayuan Wu   +9 more
doaj   +1 more source

Atypical Carcinoid of Larynx: A Case Study and a Brief Review [PDF]

Journal of Clinical and Diagnostic Research, 2014
Atypical Carcinoids, Malignancy arising from neuroendocrine cells are among the non–Epidermoid cancers of larynx. The present study reports an interesting and rare case of atypical carcinoid of larynx.
P. Dhavala Kumar, Vijayendra Simha N, Sreenivas N   +2 more
doaj   +1 more source

Human larynx motor cortices coordinate respiration for vocal-motor control

NeuroImage, 2021
Vocal flexibility is a hallmark of the human species, most particularly the capacity to speak and sing. This ability is supported in part by the evolution of a direct neural pathway linking the motor cortex to the brainstem nucleus that controls the ...
Michel Belyk, Rachel Brown, Deryk S. Beal, Alard Roebroeck, Carolyn McGettigan, Stella Guldner, Sonja A. Kotz   +6 more
doaj   +1 more source

The Effect of NNK, A Tobacco Smoke Carcinogen, on the miRNA and Mismatch DNA Repair Expression Profiles in Lung and Head and Neck Squamous Cancer Cells

Cells, 2020
Tobacco smoking is a common risk factor for lung cancer and head and neck cancer. Molecular changes such as deregulation of miRNA expression have been linked to tobacco smoking in both types of cancer.
Sotirios G. Doukas, Dimitra P. Vageli, George Lazopoulos, Demetrios A. Spandidos, Clarence T. Sasaki, Aristidis Tsatsakis   +5 more
doaj   +1 more source

A 10-Year Study on Larynx Preservation Compared With Surgical Resection in Patients With Locally Advanced Laryngeal and Hypopharyngeal Cancers

Frontiers in Oncology, 2020
BackgroundFew reports from China provide confirmed evidence of the effectiveness of the larynx preservation strategy compared with surgery on the treatment of laryngeal and hypopharyngeal cancers.
Xuan Su, Hui-Chan He, Zu-Lu Ye, Da-Lei Zhou, Qing Liu, Xin-Hua Yang, Ya-Kang Long, Tao Tang, Jiang-Jun Ma, Bo-Heng Xu, Wei-Chao Chen, Cai-Yun He, An-Kui Yang   +12 more
doaj   +1 more source

In Vivo Short-Term Topical Application of BAY 11-7082 Prevents the Acidic Bile–Induced mRNA and miRNA Oncogenic Phenotypes in Exposed Murine Hypopharyngeal Mucosa

Neoplasia: An International Journal for Oncology Research, 2018
PURPOSE: Bile-containing gastroesophageal reflux may promote cancer at extraesophageal sites. Acidic bile can accelerate NF-κB activation and molecular events, linked to premalignant changes in murine hypopharyngeal mucosa (HM). We hypothesize that short-
Clarence T. Sasaki, Sotirios G. Doukas, Dimitra P. Vageli   +2 more
doaj   +1 more source

Biliary tumorigenic effect on hypopharyngeal cells is significantly enhanced by pH reduction

Cancer Medicine, 2019
Biliary reflux has been considered a potential risk factor in upper aerodigestive tract malignancies. It is not yet clearly known how pH affects the bile‐induced activation of NF‐κB and its related oncogenic pathway previously linked to hypopharyngeal ...
Sotirios G. Doukas, Bruno Cardoso, Jacob I. Tower, Dimitra P. Vageli, Clarence T. Sasaki   +4 more
doaj   +1 more source

A rare case of coin impaction in larynx in an adult

Clinics and Practice, 2011
Impaction of foreign body in larynx is reported exclusively in paediatric population only. Moreover impaction of coin in larynx has never been reported previously. With this background, we report a rare case of coin impaction in larynx in a healthy adult.
Gautam Bir Singh, Anil K Rai, Hukum Singh, Anubha Varun   +3 more
doaj   +1 more source