Results 31 to 40 of about 9,922,164 (241)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Molecular dynamics studies of ultrafast laser-induced phase and structural change in crystalline silicon [PDF]

, 2012
In this work, thermodynamic phenomena in crystalline silicon irradiated by an ultrafast laser pulse were studied using the method of molecular dynamics simulations. The Stillinger-Weber potential was used to model the crystalline silicon. The temperature
Yang, Chengjuan, Xu, Xianfan, Wang, Yaguo   +2 more
core   +1 more source

Impacts of Ambient and Ablation Plasmas on Short- and Ultrashort-Pulse Laser Processing of Surfaces

Micromachines, 2014
In spite of the fact that more than five decades have passed since the invention of laser, some topics of laser-matter interaction still remain incompletely studied. One of such topics is plasma impact on the overall phenomenon of the interaction and its
Nadezhda M. Bulgakova, Alexei N. Panchenko, Vladimir P. Zhukov, Sergey I. Kudryashov, Antonio Pereira, Wladimir Marine, Tomas Mocek, Alexander V. Bulgakov   +7 more
doaj   +1 more source

A Review on Ultrafast Laser Microwelding of Transparent Materials and Transparent Material–Metals

Metals, 2023
Transparent hard and brittle (THB) materials have generated significant interest due to their excellent properties, such as wide spectral transmittance, heat resistance, chemical inactivity and high mechanical strength. To further explore the application
Jiayi Xu, Qing Jiang, Jin Yang, Jiangmei Cui, Yixuan Zhao, Min Zheng, J. P. Oliveira, Zhi Zeng, Rui Pan, Shujun Chen   +9 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Experimental and numerical study of laser-assisted machining of Ti6Al4V titanium alloy [PDF]

, 2014
Laser-assisted machining combines several experimental parameters such as cutting speed, feed rate, depth of cut, laser power and distance between tool rake face and the laser beam axis.
GERMAIN, Guénaël, HAMDI, Hédi, AYED, Yessine, BEN SALEM, Wacef   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Melt Pool and Keyhole Behavior Analysis for Deep Penetration Laser Welding [PDF]

, 2010
One usually defines the main characteristic of the welding performances of a given laser system by its “penetration curve” that corresponds to the welding depth as a function of the welding speed Vw for a given set of operating parameters.
R Fabbro, Fabbro, R, FABBRO, Rémy
core   +1 more source

In-situ defect detection and material property evaluationin additive manufacturing using acoustic signal and machinelearning

e-Journal of Nondestructive Testing
In-situ monitoring is crucial for detecting defects and estimating material properties to ensure the quality of printed parts in additive manufacturing. Acoustic signals produced during the interaction between the laser and material contain critical
Abdullah Bin Zainal, Zheng Jie Tan, Saritha Samudrala, Zi Wen Tham, Lei Zhang, Santhakumar Sampath   +5 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source