Results 61 to 70 of about 205,872 (218)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Laser-Induced Damage Features and Flow Interference of Coating Materials in Ma=6 Airflows

气体物理
Aimed at the new application scenario of laser, a test platform was established to study the coating material da-mage features induced by the interaction of the Ma=6 tangential air flow and the continuous laser irradiation.
Jian LIN, Lili LIU, Hongbo LU, Shuai WEN, Haiyan LI, Hongzhi LU, Song FU   +6 more
doaj   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Physical twin of an industrial quad-laser powder bed fusion machine for high-speed multi-modal sensing measurements

Materials & Design
To faithfully capture the laser-material interaction and subsequent process dynamics during the industrial laser powder bed fusion process, we developed a Quad-laser in situ and operando process replicator (or the Quad-ISOPR) – a physical twin that ...
Samy Hocine, Sebastian Marussi, Andrew Farndell, Elena Ruckh, Rubén Lambert-Garcia, Anna C.M. Getley, Kwan Kim, Nick Jones, Maureen Fitzpatrick, Marta Majkut, Alexander Rack, Peter D. Lee, Chu Lun Alex Leung   +12 more
doaj   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth, Tomáš Babinský, Jan Lars Riedel, Wen Hao Kan, Aijun Huang, Martin Heilmaier, Ivo Šulák   +6 more
wiley   +1 more source

Acoustic emission during the millisecond laser-optical glass interaction assisted by the nanosecond laser

AIP Advances, 2018
A hydrophone is used to detect the acoustic emission for the combined pulsed laser (CPL)-BK7 glass interaction. The CPL is composed of a nanosecond (ns) laser and a millisecond (ms) laser, which are separated with a certain period of time.
Y. Pan, Z. Wu, Y. Sun, H. Zhang, Z. Shen, J. Lu, X. Ni, B. Wang   +7 more
doaj   +1 more source

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

High Speed Pump-Probe Apparatus for Observation of Transitional Effects in Ultrafast Laser Micromachining Processes

Micromachines, 2015
A pump-probe experimental approach has been shown to be a very efficient tool for the observation and analysis of various laser matter interaction effects.
Ilya Alexeev, Johannes Heberle, Kristian Cvecek, Konstantin Yu. Nagulin, Michael Schmidt   +4 more
doaj   +1 more source

Fatigue Crack Initiation and Growth in Nanocrystalline Ni at Multiple Length‐Scales

Advanced Engineering Materials, EarlyView.
Overview of miniaturized in situ SEM fatigue setup and resultant fatigue crack growth data for nanocrystalline Ni. The presented study focuses on the analysis of fatigue crack growth rate (FCGR) in focused ion beam‐notched microcantilevers prepared from nanocrystalline (NC) Ni as a model material.
Igor Moravcik, Alexander Jelinek, Markus Alfreider, Jutta Luksch, Anton Hohenwarter, Florian Schaefer, Christian Motz, Daniel Kiener   +7 more
wiley   +1 more source

High‐Temperature Nanoindentation of Metals: Assessing Thermal Drift, Frame Compliance, and Chemical Composition Effects on the Reported Mechanical Properties

Advanced Engineering Materials, EarlyView.
Do not let thermal drift and instrument artifacts deceive high‐temperature nanoindentation results. We compare classical Oliver–Pharr and automatic image recognition analyses across steels and a Ni alloy to quantify these effects. Accounting for artifacts reveals systematic softening with temperature, while Cr and Ni additions boost resistance ...
Velislava Yonkova, Steffen Brinckmann, Ruth Schwaiger   +2 more
wiley   +1 more source