Results 61 to 70 of about 5,376,921 (346)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Journal of Materials Research and Technology, 2022 The laser ablation of aluminum alloy 6061 was studied both experimentally and by computational modeling in this work. Six variations of the number of pulses of irradiation (1, 5, 10, 20, 50, and 100 pulses) combined with four different laser fluence (2.0
Zhang Peng +6 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
, 2001 The mechanism of ablation of solids by intense femtosecond laser pulses is described in an explicit analytical form. It is shown that at high intensities when the ionization of the target material is complete before the end of the pulse, the ablation ...
A. V. Rode +5 more
core +1 more source
Theoretical fundamentals of short pulse laser–metal interaction: A review
Nanotechnology and Precision Engineering, 2020 Short and ultrashort pulse lasers offer excellent advantages in laser precision machining mainly because of their high pulse energy and low ablation threshold.
Xinxin Li, Yingchun Guan
doaj +1 more source
Journal of Materials Research and Technology, 2022 Temporally shaped femtosecond laser machining is a flexible and effective method to improve the efficiency and quality of cooling film holes. This study investigated the ablation of nickel-based superalloy by double-pulse femtosecond laser with different
Zhicheng Chen +5 more
doaj +1 more source
The Effects of Laser Parameters and the Ablation Mechanism in Laser Ablation of C/SiC Composite
Materials, 2019 The effects of laser parameters and the ablation mechanism in laser ablation of a carbon fiber reinforced silicon carbide (C/SiC) composite are investigated in the present study.
S. Pan +4 more
semanticscholar +1 more source