Results 111 to 120 of about 154,078 (299)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Solar-Pumped Ce:Nd:YAG Laser Amplifier Design

Energies
A solar-pumped Ce:Nd:YAG laser amplifier design is proposed to address the challenge of scaling output power in solar-pumped laser oscillators while maintaining high beam quality.
Joana Almeida, Bruno D. Tibúrcio, Hugo Costa, Cláudia R. Vistas, Dawei Liang   +4 more
doaj   +1 more source

Laser‐Based Sculpturing of Embedded Ultrathin Metal‐Oxide Nanopores for Enhanced Biomolecular Sensing

Advanced Functional Materials, EarlyView.
Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby, Yulia Marom, Guocong Lin, Aleksandra Baron‐Wiechec, Amit Meller   +4 more
wiley   +1 more source

20 kW Monolithic Fiber Amplifier With Directly Dual-Wavelength Laser Diodes Counter Pumping

IEEE Photonics Journal
In this study, we demonstrate a high-power ytterbium-doped fiber laser (YDFL) based on laser diodes (LDs) directly pumping scheme. Tandem pumping and LD direct pumping are two common schemes for generating high-brightness laser output in YDFL.
Xiangming Meng, Fengchang Li, Jinbao Chen, Xiaoming Xi, Baolai Yang, Peng Wang, Zhiyong Pan, Zhiping Yan, Hanwei Zhang, Xiaolin Wang, Zefeng Wang   +10 more
doaj   +1 more source

Laser Cooled High-Power Fiber Amplifier

, 2009
A theoretical model for laser cooled continuous-wave fiber amplifier is presented. The amplification process takes place in the Tm3+-doped core of the fluoride ZBLAN (ZrF4-BaF2-LaF3-AlF3-NaF) glass fiber. The cooling process takes place in the Yb3+:ZBLAN
Nemova, Galina
core  

Spectrally Tunable 2D Material‐Based Infrared Photodetectors for Intelligent Optoelectronics

Advanced Functional Materials, EarlyView.
Intelligent optoelectronics through spectral engineering of 2D material‐based infrared photodetectors. Abstract The evolution of intelligent optoelectronic systems is driven by artificial intelligence (AI). However, their practical realization hinges on the ability to dynamically capture and process optical signals across a broad infrared (IR) spectrum.
Junheon Ha, Yingshan Ma, Yong Nam An, Sung‐Un An, Hyeon Hak Jung, Suvi‐Tuuli Varjamo, Jiwon Yoo, Junho Min, Hanvit Kim, Faisal Ahmed, Sang Hoon Chae, Young Min Song, Weiwei Cai, Tawfique Hasan, Zhipei Sun, Dong‐Ho Kang, Hyeon‐Jin Shin, Yunyun Dai, Hoon Hahn Yoon   +18 more
wiley   +1 more source

Performance of alumina-supported Pt catalysts in an electron-beam-sustained CO2 laser amplifier [PDF]

The performance of an alumina-supported Pt catalyst system used to maintain the gas purity in an electron-beam-sustained (636) isotope CO2 laser amplifier has been tested.
Cunningham, D. L., Jones, P. L., Miyake, C. I., Moody, S. E.   +3 more
core   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

2.05 μm high-energy thulium-doped fibre amplifier based on backward pumping

Scientific Reports
We demonstrate a thulium (Tm)-doped fibre amplifier using a Ho: GdVO4 solid-state laser as the master oscillator operating at 2048.53 nm. In experiment, a novel spatial coupling system was used, combining a single lens with a curved end cap to simplify ...
Chao Yang, Bowen Zheng, Junyu Huang, Xin Li, Yongliang Li, Keyan Dong, Youlun Ju   +6 more
doaj   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source