Results 51 to 60 of about 154,423 (300)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Transformation From Conventional Dissipative Solitons to Amplifier Similaritons in All-Normal Dispersion Mode-Locked Fiber Lasers

IEEE Photonics Journal, 2018
We report the numerical demonstration of the transformation from dissipative solitons to amplifier similaritons in an all-normal dispersion ultrafast fiber laser for the first time.
Yueqing Du, Xuewen Shu
doaj   +1 more source

A High Power Frequency-Stabilized Tunable Two-Frequency Diode Laser System for the Generation of Coherent THz-Waves by Photomixing [PDF]

, 1998
A tunable two-frequency high-power diode laser system at 850 nm for terahertz (Thz)-wave generation by photomixing in low-temperature-grown GaAs photo-conductors has been developed. The difference frequency is obtained through a three laser system, where
Blake, Geoffrey A., Chen, Pin, Matsuura, Shuji, Pearson, J. C., Pickett, Herbert M.   +4 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Thermal-stress-induced birefringence management of complex laser systems by means of polarimetry

Scientific Reports, 2022
The novel method of the thermally-induced polarization changes driven power losses (TIPCL) analysis in the complex laser systems has been developed. The measurement has been tested on the amplifier chain of the 100 J / 10 Hz laser system ‘Bivoj’ operated
Ondřej Slezák, Magdalena Sawicka-Chyla, Martin Divoký, Jan Pilař, Martin Smrž, Tomáš Mocek   +5 more
doaj   +1 more source

Fiber-integrated frequency-doubling of a picosecond Raman laser to 560 nm [PDF]

, 2015
We report the development of a fiber-integrated picosecond source at 560 nm by second harmonic generation of a Raman fiber laser. A picosecond ytterbium master oscillator power fiber amplifier is used to pulse-pump a Raman amplifier, which is seeded by a
kelleher, EJR, Legg, T, murray, RT, popov, SV, Runcorn, T, taylor, JR   +5 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Low noise amplication of an optically carried microwave signal: application to atom interferometry [PDF]

, 2010
In this paper, we report a new scheme to amplify a microwave signal carried on a laser light at $\lambda$=852nm. The amplification is done via a semiconductor tapered amplifier and this scheme is used to drive stimulated Raman transitions in an atom ...
A. Gauguet, A. Landragin, A.J. Seeds, B. Canuel, C. Daussy, C.J. Bordé, C.J. Bordé, D.S. Weiss, F. Kéfélian, G. Ferrari, G. Santarelli, G.P. Agrawal, J.L. Hall, K. Moler, K. Takase, L. Goldberg, L. Morvan, M. Kasevich, M.J. O’Mahony, P. Cheinet, P. Cheinet, R. Wynands, R.A. Nyman, T. Lévèque, T. Müller, W. Chaibi, X. Baillard   +26 more
core   +5 more sources

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

On the Lightweight Potential of Laser Additive Manufactured NiTi Triply Periodic Minimal Sheet Lattices

Advanced Engineering Materials, EarlyView.
This study explores the lightweight potential of laser additive‐manufactured NiTi triply periodic minimal surface sheet lattices. It systematically investigates the effects of relative density and unit cell size on surface quality, deformation recovery, compression behavior, and energy absorption.
Haoming Mo, Shuo Qu, Shiming Gao, Xu Song   +3 more
wiley   +1 more source