Results 111 to 120 of about 81,055 (346)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Safety and Efficacy of Ureteroscopic Treatment for Ureteral and Renal Stones in Patients of Cirrhosis with Coagulopathy: A Multicenter Experience

European Urology Open Science
Background and objective: Upper urinary tract stone treatment in cirrhotic patients with coagulopathy is often delayed due to concerns about bleeding and excessive perioperative management.
Jiaxing Li, Xin Zhang, Meng-Hua Wu, Hui Liu, Xin Zheng   +4 more
doaj   +1 more source

Alternative Management of a Pediatric Case of Hemorrhagic Cystitis due to BK Virus: Use of Thulium Laser Coagulation. [PDF]

Eur Urol Open Sci, 2021
Aydogan TB, Binbay M.
europepmc   +1 more source

Operation and performance of the Ciba-Corning 512 coagulation monitor during parabolic flight [PDF]

The goal was to assess the functionality and evaluate the procedures and operations required to operate the Ciba-Corning 512 Coagulation Monitor during parabolic flight. This monitor determines the clotting characteristics of blood. The analyzer operates
Gocke, Robyn, Greenthaner, Nancy K., Lloyd, Charles W.   +2 more
core   +1 more source

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

Comprehensive Metabolomic Profiling of Cord Blood and Placental Tissue in Surviving Monochorionic Twins Complicated by Twin-Twin Transfusion Syndrome With or Without Fetoscopic Laser Coagulation Surgery: A Retrospective Cohort Study. [PDF]

Front Bioeng Biotechnol, 2022
Liu T, Wen L, Huang S, Han TL, Zhang L, Fu H, Li J, Tong C, Qi H, Saffery R, Baker PN, Kilby MD.   +11 more
europepmc   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Seeing the unseen: Laser speckles as a tool for coagulation tracking

Applied Rheology
The ability to measure protein functionality is critical for the development of plant-based products, particularly with respect to gelation behavior, which is vital for food structure and texture. Small amplitude oscillatory shear (SAOS) tests remain the
Haessig Christoph, Møller Flemming
doaj   +1 more source

THE EXPERIENCE OF ORGANIZING COLLABORATIVE WORK OF ORENBURG BRANCH OF S. FYODOROV EYE MICROSURGERY FEDERAL STATE INSTITUTION AND ORENBURG REGIONAL PERINATAL CENTRE FOR THE CONTROL OF RETINOPATHY OF PREMATURITY

Сибирский научный медицинский журнал, 2019
The purpose of the study is to increase the efficiency of delivering high-tech eye care to the infants of Orenburg and the Orenburg region.Material and methods.
A. D. Chuprov, E. K. Malgina
doaj   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source