Results 51 to 60 of about 307,922 (287)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A multi-photon magneto-optical trap

, 2009
We demonstrate a Magneto-Optical Trap (MOT) configuration which employs optical forces due to light scattering between electronically excited states of the atom.
Brown, Roger, Phillips, William D., Plisson, Thomas, Porto, J. V., Wu, Saijun   +4 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

2D transverse laser cooling of a hexapole focused beam of cold BaF molecules

Communications Physics
Laser cooling of molecules is a powerful technique for producing cold, slow beams for precision measurements and quantum control, yet its implementation remains challenging due to molecular complexity.
J. W. F. van Hofslot, I. E. Thompson, A. Touwen, N. Balasubramanian, R. Bause, H. L. Bethlem, A. Borschevsky, T. H. Fikkers, S. Hoekstra, S. A. Jones, J. E. J. Levenga, M. C. Mooij, H. Mulder, B. A. Nijman, E. H. Prinsen, B. J. Schellenberg, L. van Sloten, R. G. E. Timmermans, W. Ubachs, J. de Vries, L. Willmann, On behalf of the NL-eEDM collaboration   +21 more
doaj   +1 more source

Remark on laser linewidth hazard in opto-mechanical cooling

, 2008
I discuss the robustness of the pumped cavity dynamics against phase diffusion of the laser and conclude that opto-mechanical cooling has extreme sensitivity compared to laser cooling of atoms. Certain proposals of ground state opto-mechanical cooling by
Diósi, Lajos
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Disk Laser Welding of Car Body Zinc Coated Steel Sheets / Spawanie Laserem Dyskowym Blach Ze Stali Karoseryjnej Ocynkowanej

Archives of Metallurgy and Materials, 2015
Autogenous laser welding of 0.8 mm thick butt joints of car body electro-galvanized steel sheet DC04 was investigated. The Yb:YAG disk laser TruDisk 3302 with the beam spot diameter of 200 μm was used.
Lisiecki A., Burdzik R., Siwiec G., Konieczny Ł., Warczek J., Folęga P., Oleksiak B.   +6 more
doaj   +1 more source

Narrow Line Cooling and Momentum-Space Crystals

, 2004
Narrow line laser cooling is advancing the frontier for experiments ranging from studies of fundamental atomic physics to high precision optical frequency standards.
A. Noble, Andrew D. Ludlow, H. J. Metcalf, H. Katori, Jun Ye, Martin M. Boyd, T. Loftus, Tetsuya Ido, Thomas H. Loftus, Y. Castin   +9 more
core   +1 more source

Cool Laser Pulses [PDF]

Laser Technik Journal, 2014
AbstractDuring the past decades pulsed laser systems have motivated many novel laser material applications. Nowadays ultrashort pulse (USP) lasers are routinely used for machining and processing high‐tech materials like glass, sapphire or ceramics and allow the production of small and powerful smart phones, high efficient solar cells or medical devices.
openaire   +1 more source

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett, Syeda Amrah Hashmi, Amaan Qureshi, Heather Spader, Shayan Moosa, Ifrah Zawar   +5 more
wiley   +1 more source