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Laser interference microscopy in erythrocyte study

Journal of Applied Physics, 2009
With the laser interference microscopy (LIM) technique, one can measure phase height of cells—a variable proportional to the cell thickness and the difference in the refractive indices of the cell and the surrounding medium. This makes functional optical cell imaging possible, and estimation of shape, thickness, and area of erythrocytes feasible.
A I Yusipovich   +2 more
exaly   +2 more sources

Laser Interference Microscopy for Nanobiotechnologies

Bio-Medical Engineering, 2013
Interference microscopy is widely used in different areas of science for comprehensive study of optical and geometric properties of various microand nanoobjects. The fact that phase imaging makes it possible to overcome the classical resolution threshold has been well known since the 1950s (1).
K V Indukaev, Indukaev K V
exaly   +3 more sources

Non-invasive study of nerve fibres using laser interference microscopy

Philosophical Transactions Series A, Mathematical, Physical, and Engineering Sciences, 2008
This paper presents the results of a laser interference microscopy study of the morphology and dynamical properties of myelinated nerve fibres. We describe the principles of operation of the phase-modulated laser interference microscope and show how this novel technique allows us to obtain information non-invasively about the internal structure of ...
G V Maksimov   +2 more
exaly   +4 more sources

Evaluation of erythrocyte shape and status by laser interference microscopy

Bulletin of Experimental Biology and Medicine, 2008
The area, thickness, and volume of erythrocytes of different types (discocytes, stomatocytes, and echinocytes) from normal subjects and coronary patients were studied by laser interference microscopy. Increase of pH value leading to the stomatocyte-discocyte-echinocyte transformations resulted in a slight decrease of cell volume.
A I Yusipovich, E Yu Parshina, G G Levin
exaly   +3 more sources

New possibilities for the study of microbiological objects by laser interference microscopy

Measurement Techniques, 2012
A method using laser interference microscopy has been proposed for studying the morphological and functional state of bacterial cells. Using LIM permits rapid determination of cell and subcellular structure and the physiological state of cells as well as investigation of the structure of bacterial communities.
A I Yusipovich, G G Levin, G V Maksimov
exaly   +2 more sources

Study of cancer and normal cells dynamics based on laser interference microscopy

AIP Conference Proceedings, 2020
The work is devoted to the study of dynamics of living breast human cells in cancerous and normal states using laser microscopy. Analysis of optical cell thickness fluctuations was conducted to characterize multiscale correlation properties in terms of temporal invariants to support a criterion for differentiation of cancer and normal cells as the ...
V V Grishko
exaly   +2 more sources

A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy

Bone, 2001
Osteocytes are the most numerous cells in bone, embedded within the mineralized bone matrix. Their slender cytoplasmic processes form a complex intercellular network. In addition, these processes are thought to be important structures in the response to mechanical stress.
Hiroshi Kamioka
exaly   +3 more sources

Spectrally resolved laser interference microscopy

Laser Physics Letters, 2018
Abstract We developed a new quantitative phase microscopy technique, namely, spectrally resolved laser interference microscopy (SR-LIM), with which it is possible to quantify multi-spectral phase information related to biological specimens without color crosstalk using a color CCD camera. It is a single shot technique where sequential
Ankit Butola   +4 more
openaire   +1 more source

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