Results 51 to 60 of about 75,493 (303)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Avaliação dos dados laser scanner para determinar modelos de terreno em áreas cobertas por floresta ombrófila densa alterada na Amazônia [PDF]

open access: yes, 2007
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Civil.Em florestas, informações tridimensionais de terreno têm sido obtidas por sensores como os de radar, os fotogramétricos ou por ...
Vargas, Rosane Maciel de Araújo
core  

DLR VR-SCAN: A versatile and robust miniaturized laser scanner for short range 3D-modelling and exploration in robotics

open access: yes, 2011
Precise and robust perception of the environment is crucial for highly integrated and autonomous robot systems. In this paper the dedicated design of a triangulation based laser range scanner optimized for 3D-modelling and autonomous exploration in ...
Hacker, Franz   +9 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Ajustamento simultâneo do bloco de faixas do laser scanner aerotransportado (ALS) [PDF]

open access: yes, 2008
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Civil, Florianópolis, 2008A discrepância vertical na zona de sobreposição lateral é uma distorção da medida original de difícil ...
Temba, Plinio da Costa
core  

Smartphone 3D Scanning Technology and 3D Semi-Synthetic Data for Processing Infant Head Deformities Using Artificial Intelligence

open access: yesSensors
Background: Early assessment of cranial deformities in newborns, such as plagiocephaly, brachycephaly, dolichocephaly, turricephaly, and trigonocephaly, requires precise and non-invasive methods.
Omar C. Quispe-Enriquez   +1 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

O Potencial do laser scanner terrestre para o inventário do patrimônio arquitetônico [PDF]

open access: yes, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Civil.Mediante a necessidade do Instituto do Patrimônio Histórico e Artístico Nacional (IPHAN) padronizar os dados espaciais ...
Beirão, Carla Castello Branco
core  

Evaluation and comparison of surface macrotexture and friction measurement methods

open access: yesJournal of Civil Engineering and Management, 2013
Two- and three-dimensional macrotexture characteristics of various surfaces were measured using five different testing methods including sand patch method, laser profiler, laser texture scanner, circular texture meter, and x-ray computed tomography (CT ...
Halil Sezen, Nicholas Fisco
doaj   +1 more source

Comparison of a three dimensional laser scanner with coordinate measuring machine in arch drawing [PDF]

open access: yesIranian Journal of Orthodontics, 2012
Background and aim: The aim of present study was to compare the 4th degree polynomials’ drawings generated by the invented laser scanner and ones generated by a CMM. Materials and methods: This diagnostic experimental study was conducted on maxillary and
Mahtab Nouri   +2 more
doaj   +1 more source

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