Results 1 to 10 of about 379,616 (340)

Infrared spectroscopic laser scanning confocal microscopy for whole-slide chemical imaging [PDF]

open access: yesNature Communications, 2023
Chemical imaging, especially mid-infrared spectroscopic microscopy, enables label-free biomedical analyses while achieving expansive molecular sensitivity. However, its slow speed and poor image quality impede widespread adoption. We present a microscope
Kevin Yeh   +13 more
doaj   +3 more sources

Cryo-laser scanning confocal microscopy of diffusible plant compounds [PDF]

open access: yesPlant Methods, 2018
Background The in vivo observation of diffusible components, such as ions and small phenolic compounds, remains a challenge in turgid plant organs. The analytical techniques used to localize such components in water-rich tissue with a large field of view
Kevin Vidot   +4 more
doaj   +3 more sources

Circularly polarised luminescence laser scanning confocal microscopy to study live cell chiral molecular interactions. [PDF]

open access: yesNat Commun, 2022
The molecular machinery of life is founded on chiral building blocks, but no experimental technique is currently available to distinguish or monitor chiral systems in live cell bio-imaging studies.
Stachelek P   +3 more
europepmc   +2 more sources

Corneal In Vivo Laser-Scanning Confocal Microscopy Findings in Dry Eye Patients with Sjögren's Syndrome. [PDF]

open access: yesDiagnostics (Basel), 2020
Purpose: To evaluate the changes in cornea in Sjögren’s syndrome (SS) with a novel confocal microscopy device. Methods: Twenty-three right eyes of patients with SS (23 women; mean age, 65.4 ± 11.4 years) and 13 right eyes of 13 age- and sex-matched ...
Matsumoto Y   +5 more
europepmc   +2 more sources

Confocal Laser Scanning Microscopy [PDF]

open access: yesBioTechniques, 1999
Many technological advancements of the past decade have contributed to improvements in the photon efficiency of the confocal laser scanning microscope (CLSM).
Stephen W. Paddock
doaj   +3 more sources

Correlative atomic force microscopy quantitative imaging-laser scanning confocal microscopy quantifies the impact of stressors on live cells in real-time. [PDF]

open access: yesSci Rep, 2018
There is an urgent need to assess the effect of anthropogenic chemicals on model cells prior to their release, helping to predict their potential impact on the environment and human health.
Bhat SV   +5 more
europepmc   +2 more sources

QUANTITATIVE CONFOCAL LASER SCANNING MICROSCOPY

open access: yesImage Analysis and Stereology, 2011
This paper discusses recent advances in confocal laser scanning microscopy (CLSM) for imaging of 3D structure as well as quantitative characterization of biomolecular interactions and diffusion behaviour by means of one- and two-photon excitation.
Merete Krog Raarup   +1 more
doaj   +5 more sources

In Vivo Laser Scanning Confocal Microscopy of Human Meibomian Glands in Aging and Ocular Surface Diseases. [PDF]

open access: yesBiomed Res Int, 2016
Meibomian glands (MGs) play a crucial role in the ocular surface homeostasis by providing lipids to the superficial tear film. Their dysfunction destabilizes the tear film leading to a progressive loss of the ocular surface equilibrium and increasing the
Fasanella V   +6 more
europepmc   +2 more sources

Detection of Gold Nanoparticles Aggregation Growth Induced by Nucleic Acid through Laser Scanning Confocal Microscopy [PDF]

open access: yesSensors, 2016
The gold nanoparticle (GNP) aggregation growth induced by deoxyribonucleic acid (DNA) is studied by laser scanning confocal and environmental scanning electron microscopies. As in the investigated case the direct light scattering analysis is not suitable,
Ramla Gary   +4 more
doaj   +2 more sources

Diagnosis of Basal Cell Carcinoma with Ex-vivo Confocal Laser Scanning Microscopy in a Real-life Setting

open access: yesActa Dermato-Venereologica, 2023
Ex-vivo confocal laser scanning microscopy provides a rapid alternative to routine histological processing using haematoxylin and eosin-stained sections. Previous studies suggest high diagnostic accuracy in basal cell carcinoma.
Stephan Forchhammer   +6 more
doaj   +1 more source

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