Results 231 to 240 of about 4,592,774 (277)

A Novel Sparse Cellular Labeling System with Tunable Gradients and Long‐Term Stability

open access: yesAdvanced Science, EarlyView.
The Tri‐M (Multi‐recombinase, Multi‐recognition site, and Multi‐nested) sparse cellular labeling system, built upon competitive recombination, integrates transgenic mice with viral injection to achieve tunable and long‐term stable sparse labeling of specific cell types with region selectivity, from sparse populations to individual cells, facilitating ...
Xiaomei Tang   +17 more
wiley   +1 more source

AI‐Powered, Temperature‐Resolved Centrifugal Microfluidics for Rapid 3D Phase‐Diagram Generation of Biomolecular Condensates

open access: yesAdvanced Science, EarlyView.
By merging centrifugal microfluidics, precise temperature control, and AI image recognition, T‐PhaseMap transforms biomolecular condensate phase mapping into a rapid, temperature‐resolved workflow. It generates 3D composition–temperature phase diagrams within 30 min, resolves four phase states, and uncovers temperature‐dependent heparin sodium ...
Jiashuo Li   +6 more
wiley   +1 more source

Perfusion Mapping of Flaps Using Indocyanine Green Fluorescence Angiography and Laser Speckle Contrast Imaging. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Zötterman J   +4 more
europepmc   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

Mechanophore‐Based Multichannel Colorimetric Force Sensors: Ultrasound‐Driven Stress and Strain Quantification

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mechanophores with mechanochromic properties have attracted significant attention as force‐responsive materials for structural sensing. However, their applications remain mainly limited to qualitative force visualization, as direct and quantitative extraction of mechanical parameters such as stress and strain from mechanochromic responses has ...
Seungo Baek   +8 more
wiley   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

open access: yesAdvanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy