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Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system. [PDF]

APL Bioeng
Hsieh MC, Chang CY, Hsu CH, Lin YR, Hsieh PY, Ching CT, Liao LD.   +6 more
europepmc   +1 more source

Laser Speckle Contrast Imaging in Neurosurgery: A Systematic Review [PDF]

World Neurosurgery, 2023
Intraoperative study of blood flow in the brain vessels is among the most critical topics of modern neurosurgery. One of the promising methods for intraoperative monitoring of blood flow is laser speckle contrast imaging (LSCI). This systematic review aims to analyze the experience of using intraoperative LSCI in neurosurgical interventions.The ...
Anton Konovalov, Vadim Gadzhiagaev, Dmitry Stavtsev   +2 more
exaly   +4 more sources

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Laser Speckle Contrast Imaging: Theory, Instrumentation and Applications

IEEE Reviews in Biomedical Engineering, 2013
Laser Speckle Contrast Imaging (LSCI) is a wide field of view, non scanning optical technique for observing blood flow. Speckles are produced when coherent light scattered back from biological tissue is diffracted through the limiting aperture of focusing optics.
Janaka Senarathna, Abhishek Rege, Nan Li   +2 more
exaly   +3 more sources

Detrimental effects of speckle-pixel size matching in laser speckle contrast imaging

Optics Letters, 2008
Through a series of simulations and experiments, we demonstrate that the frequently cited criterion of matching speckle size to detector element (pixel) size in laser speckle contrast imaging (LSCI) has the detrimental effect of reducing the contrast and thereby decreasing the variation in the laser speckle contrast image.
Sean J Kirkpatrick, Donald D Duncan
exaly   +3 more sources

A Miniaturized Platform for Laser Speckle Contrast Imaging

IEEE Transactions on Biomedical Circuits and Systems, 2012
Imaging the brain in animal models enables scientists to unravel new biological insights. Despite critical advancements in recent years, most laboratory imaging techniques comprise of bulky bench top apparatus that require the imaged animals to be anesthetized and immobilized.
Janaka Senarathna, Kartikeya Murari, Ralph Etienne-Cummings, Nitish V. Thakor   +3 more
openaire   +2 more sources

Efficient Processing of Laser Speckle Contrast Images

IEEE Transactions on Medical Imaging, 2008
Though laser speckle contrast imaging enables the measurement of scattering particle dynamics with high temporal resolution, the subsequent processing has previously been much slower. In prior studies, generating a laser speckle contrast image required about 1 s to process a raw image potentially collected in 10 ms or less.
W. James Tom, Adrien Ponticorvo, Andrew K. Dunn 0001   +2 more
openaire   +2 more sources

Depth resolution in multifocus laser speckle contrast imaging

Optics Letters, 2021
Laser speckle contrast imaging (LSCI) can be used to evaluate blood flow based on spatial or temporal speckle statistics, but its accuracy is undermined by out-of-focus image blur. In this Letter, we show how the fraction of dynamic versus static light scattering is dependent on focus, and describe a deconvolution strategy to correct for out-of-focus ...
Shuqi Zheng, Sheng Xiao, Lisa Kretsge, Alberto Cruz-Martín, Jerome Mertz   +4 more
openaire   +2 more sources

Calibration in laser speckle contrast imaging

Biomedical Optics, 2006
We provided a novel calibration procedure in laser speckle contrast imaging that can efficiently compensate systematic errors in speckle contrast caused by speckle/pixel size mismatch and static scatters in the tissue.
Shuai Yuan, Andrew K. Dunn, David A. Boas   +2 more
openaire   +1 more source

Contrast-enhanced imaging of cerebral vasculature with laser speckle

Applied Optics, 2007
High-resolution cerebral vasculature imaging has applications ranging from intraoperative procedures to basic neuroscience research. Laser speckle, with spatial contrast processing, has recently been used to map cerebral blood flow. We present an application of the technique using temporal contrast processing to image cerebral vascular structures with ...
K, Murari, N, Li, A, Rege, X, Jia, A, All, N, Thakor   +5 more
openaire   +2 more sources

Laser speckle contrast imaging for assessment of liver microcirculation

Microvascular Research, 2013
Laser speckle contrast imaging (LSCI) is a novel technique for microcirculation imaging not previously used in the liver. The aim of the present experimental study was to evaluate the use of LSCI for assessing liver microcirculation.In six male Wistar rats, the median liver lobe was exposed through a midline laparotomy.
Sturesson, Christian, Milstein, Dan M. J., Post, Ivo C. J. H., Maas, Adrie M., van Gulik, Thomas M.   +4 more
openaire   +2 more sources