Results 81 to 90 of about 4,592,774 (277)

Reproducibility and normalization of reactive hyperemia using laser speckle contrast imaging.

PLoS ONE, 2021
BackgroundImpaired perfusion indices signal potential microvascular dysfunction preceding atherosclerosis and other cardiometabolic pathologies. Post-occlusive reactive hyperemia (PORH), a vasodilatory response following a mechanically induced ischemia ...
Behnia Rezazadeh Shirazi, Rudy J Valentine, James A Lang   +2 more
doaj   +1 more source

Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin

Advanced Healthcare Materials, EarlyView.
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi, Gülçin Arslan Azizoğlu, Mark R. Prausnitz   +2 more
wiley   +1 more source

Multiwavelength Implantable Oximeter for Wireless Monitoring of Tissue Oxygenation in the Presence of Blood Volume Changes

Advanced Healthcare Materials, EarlyView.
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky, Hugo L. Higueros‐Garcia, Sadi Loai, Samantha Unger, Jacob Trueb, Yonatan Usatinsky, Rawad Alkallas‐Valdiviezo, Noor Abu Jarad, Jonathan Wu, Hai‐Ling M. Cheng, John A. Rogers, Abraham Vázquez‐Guardado, Daniel Franklin   +12 more
wiley   +1 more source

Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity

, 2022
Laser speckle contrast imaging is a robust and versatile blood flow imaging tool in basic and clinical research for its relatively simple construction and ease of customization. One of its key features is the scalability of the imaged field of view. With
Sørensen, Charlotte M., Sorensen, Charlotte M., Sosnovtseva, Olga, Lee, Blaire, Postnov, Dmitry D.   +4 more
core   +1 more source

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

Advanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto, Pratik Kusumanchi, Jesper Guldsmed Madsen, Asbjørn Cortnum Jørgensen, Gisele Alves dos Reis Benatto, Sune Thorsteinsson, Peter Behrensdorff Poulsen, Keisuke Yonehara, Toke Bek, Stephan Sylvest Keller, Rasmus Schmidt Davidsen   +10 more
wiley   +1 more source

Laser Speckle Orthogonal Contrast Imaging Calibration by Replicating Red Blood Cell Scattering Statistics with a Moving Reference Diffuser

Photonics
Recent studies have proposed improving Laser Speckle Contrast Imaging (LSCI) by using polarimetric filtering to isolate multiply scattered photons from moving red blood cells (RBCs), an approach referred to as Laser Speckle Orthogonal Contrast Imaging ...
Xavier Orlik, Aurélien Plyer, Elise Colin   +2 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Reversible Hydration Tuning of Polar Order and Large Nonlinear Optical Response in a 2D van der Waals Crystal, LiInP2S6

Advanced Materials, EarlyView.
Hydration‐induced symmetry breaking transforms layered LiInP2S6${\rm LiInP}_2{\rm S}_6$ from a nonpolar to a chiral‐polar phase, producing a giant enhancement of non‐resonant second‐harmonic generation. The reversible tuning of polar order through molecular intercalation establishes a strategy for dynamically controlling nonlinear optical ...
Jadupati Nag, Saugata Sarker, Michael J. Waters, Safdar Imam, Himirkanti Sarkar, Anthony Richardella, James M. Rondinelli, Mercouri G. Kanatzidis, Venkatraman Gopalan   +8 more
wiley   +1 more source

Use of Laser Speckle Contrast Imaging for Successful Fingertip Replantation

Plastic and Reconstructive Surgery, Global Open, 2018
Summary:. Fingertip replantation is a technical challenge for microsurgeons. For successful fingertip replantation, it is important to monitor the replanted fingertip vascularity for the early detection and revision of vascular compromise.
Ryo Karakawa, MD, Tomoyuki Yano, MD, PhD, Hidehiko Yoshimatsu, MD, Mitsunobu Harima, MD, Koji Kanayama, MD, PhD, Takuya Iida, MD, PhD, Masayuki Sawaizumi, MD, PhD   +6 more
doaj   +1 more source