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Clinical applications of laser speckle contrast imaging: a review [PDF]

open access: yesJournal of Biomedical Optics, 2019
When a biological tissue is illuminated with coherent light, an interference pattern will be formed at the detector, the so-called speckle pattern. Laser speckle contrast imaging (LSCI) is a technique based on the dynamic change in this backscattered light as a result of interaction with red blood cells. It can be used to visualize perfusion in various
Wido Heeman   +2 more
exaly   +7 more sources

Photothermal laser speckle imaging [PDF]

open access: yesOptics Letters, 2014
The analysis of speckle contrast in a time-integrated speckle pattern enables visualization of superficial blood flow in exposed vasculature, a method we call laser speckle imaging (LSI). With current methods, LSI does not enable visualization of subsurface or small vasculature, because of optical scattering by stationary structures.
Regan, Caitlin   +2 more
openaire   +6 more sources

Laser speckle contrast imaging to assess microcirculation

open access: yesCardiology Journal, 2022
International ...
Marcin Hellmann   +2 more
doaj   +4 more sources

Handheld, point-of-care laser speckle imaging. [PDF]

open access: yesJ Biomed Opt, 2016
Laser speckle imaging (LSI) enables measurement of relative changes in blood flow in biological tissues. We postulate that a point-of-care form factor will lower barriers to routine clinical use of LSI. Here, we describe a first-generation handheld LSI device based on a tablet computer.
Farraro R, Fathi O, Choi B.
europepmc   +6 more sources

Noise in laser speckle correlation and imaging techniques

open access: yesOptics Express, 2010
We study the noise of the intensity variance and of the intensity correlation and structure functions measured in light scattering from a random medium in the case when these quantities are obtained by averaging over a finite number N of pixels of a digital camera.
S E Skipetrov   +2 more
exaly   +8 more sources

Laser speckle imaging for early detection of microbial colony forming units [PDF]

open access: yesBiomedical Optics Express, 2021
Jänis Liepinš   +2 more
exaly   +2 more sources

Line Scan Spatial Speckle Contrast Imaging and Its Application in Blood Flow Imaging

open access: yesApplied Sciences, 2021
Laser speckle imaging has been an indispensable tool for visualizing blood flow in biomedical applications. We proposed a novel design of the laser speckle imaging system, which combines confocal illumination and detection with various speckle analysis ...
E Du   +3 more
doaj   +1 more source

Speckle free laser imaging [PDF]

open access: yesConference on Lasers and Electro-Optics 2012, 2012
Many imaging applications require increasingly bright illumination sources, motivating the replacement of conventional thermal light sources with light emitting diodes (LEDs), superluminescent diodes (SLDs) and lasers. Despite their brightness, lasers and SLDs are poorly suited for full-field imaging applications because their high spatial coherence ...
Redding, Brandon   +2 more
openaire   +2 more sources

Real-Time Laser Speckle Imaging of Blood Flow with High Gray Level and High Resolution

open access: yesShanghai Jiaotong Daxue xuebao, 2023
Laser speckle contrast imaging (LSCI) is a large measurement ranging, real-time, high spatial resolution optical imaging method. Exisiting reserches show that the low gray level (8-bit) and low resolution (752×480 pixels) camera can effectively monitor ...
ZHANG Zelong, ZHANG Yingchao, WU Bo, DONG Wei, FAN Youben
doaj   +1 more source

Magnetomotive laser speckle imaging [PDF]

open access: yesJournal of Biomedical Optics, 2010
Laser speckle imaging (LSI) involves analysis of reflectance images collected during coherent optical excitation of an object to compute wide-field maps of tissue blood flow. An intrinsic limitation of LSI for resolving microvascular architecture is that its signal depends on relative motion of interrogated red blood cells.
Jeehyun, Kim   +2 more
openaire   +2 more sources

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