Results 41 to 50 of about 83,581 (314)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Recent advances in ultrafast optical parametric oscillator frequency combs [PDF]

open access: yes, 2014
We discuss recent advances in the stabilization and application of femtosecond frequency combs based on optical parametric oscillators (OPOs) pumped by femtosecond lasers at 800 and 1060 nm.
Reid, Derryck T.; id_orcid   +2 more
core   +1 more source

Compact Diode-Pumped Solid-State Laser with Intracavity Pump-Enhanced DFG Emitting at ~3.5 Microns

open access: yesPhotonics, 2023
We report a diode-pumped solid-state (DPSS) laser used for intracavity pump-enhanced difference frequency generation (DFG) to create a 3.5-micron laser. Using a 50 mm-long periodically poled lithium niobate (PPLN) crystal inside the cavity of an Nd:YVO4 ...
Liam G. K. Flannigan   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Random lasing in a short Er-doped artificial Rayleigh fiber

open access: yesResults in Physics, 2020
We report on random lasing observed with 5-m-long Er-doped fiber comprising an array of weak fiber Bragg gratings (FBGs) inscribed in the fiber core and uniformly distributed over the whole fiber length.
S.M. Popov   +5 more
doaj   +1 more source

Self-referenced frequency comb from a polarization-maintaining Er: Fiber laser based nonlinear polarization evolution

open access: yesResults in Physics, 2021
To the best of our knowledge, this paper presents the first self-referenced polarization-maintaining (PM) Er: nonlinear polarization evolution-based fiber frequency comb.
Gehui Xie   +7 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Laser-induced rotation and cooling of a trapped microgyroscope in vacuum [PDF]

open access: yes, 2013
This work was supported by the UK Engineering and Physical Sciences Research Council (EPSRC grant numbers: EP/J01771X/1 and EP/G061688/1)Quantum state preparation of mesoscopic objects is a powerful playground for the elucidation of many physical ...
Arita, Yoshihiko   +2 more
core   +1 more source

Tutorial on laser locking techniques and the manufacturing of vapor cells for spectroscopy

open access: yesNew Journal of Physics
This tutorial provides a hands-on entry point about laser locking for atomic vapor research and related research such as laser cooling. We furthermore introduce common materials and methods for the fabrication of vapor cells as a tool for this research ...
Max Mäusezahl   +2 more
doaj   +1 more source

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