Results 41 to 50 of about 83,581 (314)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Recent advances in ultrafast optical parametric oscillator frequency combs [PDF]
We discuss recent advances in the stabilization and application of femtosecond frequency combs based on optical parametric oscillators (OPOs) pumped by femtosecond lasers at 800 and 1060 nm.
Reid, Derryck T.; id_orcid +2 more
core +1 more source
Compact Diode-Pumped Solid-State Laser with Intracavity Pump-Enhanced DFG Emitting at ~3.5 Microns
We report a diode-pumped solid-state (DPSS) laser used for intracavity pump-enhanced difference frequency generation (DFG) to create a 3.5-micron laser. Using a 50 mm-long periodically poled lithium niobate (PPLN) crystal inside the cavity of an Nd:YVO4 ...
Liam G. K. Flannigan +4 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Random lasing in a short Er-doped artificial Rayleigh fiber
We report on random lasing observed with 5-m-long Er-doped fiber comprising an array of weak fiber Bragg gratings (FBGs) inscribed in the fiber core and uniformly distributed over the whole fiber length.
S.M. Popov +5 more
doaj +1 more source
To the best of our knowledge, this paper presents the first self-referenced polarization-maintaining (PM) Er: nonlinear polarization evolution-based fiber frequency comb.
Gehui Xie +7 more
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Laser-induced rotation and cooling of a trapped microgyroscope in vacuum [PDF]
This work was supported by the UK Engineering and Physical Sciences Research Council (EPSRC grant numbers: EP/J01771X/1 and EP/G061688/1)Quantum state preparation of mesoscopic objects is a powerful playground for the elucidation of many physical ...
Arita, Yoshihiko +2 more
core +1 more source
Tutorial on laser locking techniques and the manufacturing of vapor cells for spectroscopy
This tutorial provides a hands-on entry point about laser locking for atomic vapor research and related research such as laser cooling. We furthermore introduce common materials and methods for the fabrication of vapor cells as a tool for this research ...
Max Mäusezahl +2 more
doaj +1 more source

