Results 41 to 50 of about 545,503 (269)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Technology and equipment for processing diamond materials of modern electronics [PDF]

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2009
The methods of selection and sorting of diamonds according to their physical properties by modern physical methods of the analysis are developed, as well as the technologies of precision laser cutting of diamonds, their processing on a basis of ...
Mityagin A. Yu.   +2 more
doaj  

Treatment of rhinophyma using a copper vapor laser

open access: yesVestnik Dermatologii i Venerologii, 2019
Background. Rhinophyma is considered to be the most severe stage of rosacea, associated with the proliferation of the nose skin epithelium, hyperproduction of the sebaceous glands and telangiectasia.The treatment of rhinophyma remains a difficult task ...
S. V. Klyuchareva   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The layer by layer selective laser synthesis of ruby [PDF]

open access: yesScience of Sintering, 2010
In the work, features of the layer-by-layer selective laser synthesis (SLS) of ruby from an Al2O3-Cr2O3 mixture are considered depending on the irradiation power, the laser beam traverse speed, the height and amount of the backfill of powder layers.
Vlasova M.   +7 more
doaj   +1 more source

The Impact of Side-Selective Laser Tailoring of Titania Nanotubes on Changes in Photoelectrocatalytic Activity

open access: yesMicromachines, 2023
Over the last few decades, titanium(IV) oxide-based materials have gained particular attention due to their stability, corrosion resistance, photocatalytic activity under UV light, and possibilities for modification.
Katarzyna Siuzdak   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Assessment of Surface Roughness of Non-Metallic Materials during Laser Processing

open access: yesПриборы и методы измерений
Experimental studies of the surface of non-metallic materials have been carried out to determine the roughness parameters of materials such as leather, bone, wood, plastic after processing the surface of materials with a laser beam. To assess the quality
V. A. Alekseev   +3 more
doaj   +1 more source

Subthreshold micropulse yellow 577 nm laser therapy of diabetic macular oedema in rural and urban patients of south-eastern Poland

open access: yesAnnals of Agricultural and Environmental Medicine, 2017
Objectiv To evaluate the efficacy of subthreshold micropulse yellow (577 nm) laser photocoagulation in diffuse macular edema (DME) in rural and urban patients of south-eastern Poland.
Małgorzata Latalska   +3 more
doaj   +1 more source

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