Results 51 to 60 of about 545,503 (269)

Quantitative Monitoring of Tattoo Contrast Variations after 755-nm Laser Treatments in In Vivo Tattoo Models

Sensors, 2020
Laser lights have been used by dermatologists for tattoo removal through photothermal interactions. However, most clinical studies used a visual scoring method to evaluate the tattoo removal process less objectively, leading to unnecessary treatments ...
Myeongjin Kim, Suhyun Park, Hyun Uk Lee, Hyun Wook Kang   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Surface modification techniques for zirconia-based bioceramics: A review

Journal of Pharmacy and Bioallied Sciences, 2019
Zirconia is gaining interest as a ceramic biomaterial for implant applications due to its biocompatibility and desirable mechanical properties. At present, zirconia-based bioceramics is often seen in the applications of hip replacement and dental ...
Suma Karthigeyan, Arun Jaikumar Ravindran, Ramesh T R Bhat, Madhulika Naidu Nageshwarao, Sree Varun Murugesan, Vignesswary Angamuthu   +5 more
doaj   +1 more source

An evaluation of the management of hirsutism in public versus private outpatient departments in Saudi Arabia

Journal of Dermatology and Dermatologic Surgery, 2023
Background: Hirsutism is the excessive body or facial terminal (coarse) hair growth in females in a male-like pattern, carries a worldwide prevalence of 5%–20%, and requires careful evaluation and long-term management.
Malak H Aldosari, Ahmed Saleh, Abdubadie Kutubi, Asma F Al-Ruhaimi, Yara Bashawri, Arwa K Althubyani, Raneem Saleh, Hala Khalil   +7 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

On the Corrosion Properties of Aluminum 2024 Laser‐Textured Surfaces with Superhydrophilic and Superhydrophobic Wettability States

Advanced Materials Interfaces, 2023
In this work, the mechanism of the corrosion behavior of laser‐treated aluminum is studied. Two different laser techniques are used to fabricate the samples, direct laser interference patterning (DLIP) and direct laser writing (DLW), using nanosecond ...
Lis Geraldine Zschach, Robert Baumann, Flavio Soldera, Claudia Marcela Méndez, Sabine Apelt, Ute Bergmann, Andrés Fabián Lasagni   +6 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Pan-retinal photocoagulation and other forms of laser treatment and drug therapies for non-proliferative diabetic retinopathy: systematic review and economic evaluation

Health Technology Assessment, 2015
Background: Diabetic retinopathy is an important cause of visual loss. Laser photocoagulation preserves vision in diabetic retinopathy but is currently used at the stage of proliferative diabetic retinopathy (PDR).
Pamela Royle, Hema Mistry, Peter Auguste, Deepson Shyangdan, Karoline Freeman, Noemi Lois, Norman Waugh   +6 more
doaj   +1 more source

Laser treatment of retinal angiomatosis [PDF]

Eye, 1989
We have treated 26 retinal angiomas of less than 4.5 mm in size in 15 eyes using repeated applications of contiguous argon blue green laser burns. All except one of the angiomas regressed without a massive exudative response of treatment. Haemorrhage occurred in two cases but only affected the visual outcome in one eye.
C M, Lane, G, Turner, Z J, Gregor, A C, Bird   +3 more
openaire   +2 more sources