Results 41 to 50 of about 103,730 (259)

Microbial community characterization of multi-crop growouts in the XROOTS aeroponic–hydroponic system on the International Space Station

Frontiers in Microbiomes
Plant growth systems tested on the International Space Station (ISS) are small-area growth units that mostly use solid media. With NASA’s plan to send astronauts on long-duration exploration missions, there is a need to produce larger amounts of fresh ...
Christina L. M. Khodadad, Cory J. Spern, Mary E. Hummerick, Jennifer L. Gooden, Jennifer L. Gooden, Cristiana J. Morales, Raymond M. Wheeler, Orlando Melendez, Robert Morrow, John Wetzel, Ye Zhang   +10 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Panorama internacional y regional del lavado de activos y sus impactos sociales, políticos y económicos en Ecuador

Revista de Relaciones Internacionales, Estrategia y Seguridad
La investigación tiene como objetivo analizar el lavado de activos como un fenómeno social contemporáneo en los panoramas internacional y regional, y describir sus efectos sociales, políticos y económicos en Ecuador.
Edison Patricio Cisneros Corrales, Josué Israel Barragán Pacheco   +1 more
doaj   +1 more source

Predicting the risk of autoimmune thyroid disease in patients with vitiligo: Development and assessment of a new predictive nomogram

Frontiers in Endocrinology, 2023
BackgroundThis study aimed to develop an autoimmune thyroid disease (AITD) risk prediction model for patients with vitiligo based on readily available characteristics.MethodsA retrospective analysis was conducted on the clinical characteristics ...
Ze Ma, Menghan Cai, Kang Yang, Junru Liu, Tao Guo, Xiaojie Liu, Junling Zhang   +6 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Pick-and-eat space crop production flight testing on the International Space Station

Journal of Plant Interactions
Fresh, nutritious, palatable produce for crew consumption on long-duration spaceflight missions may provide health-promoting, bioavailable nutrients and enhance the dietary experience.
Jess M. Bunchek, Mary E. Hummerick, LaShelle E. Spencer, Matthew W. Romeyn, Millennia Young, Robert C. Morrow, Cary A. Mitchell, Grace L. Douglas, Raymond M. Wheeler, Gioia D. Massa   +9 more
doaj   +1 more source

Adaptive Lasso, Transfer Lasso, and Beyond: An Asymptotic Perspective

CoRR, 2023
This paper presents a comprehensive exploration of the theoretical properties inherent in the Adaptive Lasso and the Transfer Lasso. The Adaptive Lasso, a well-established method, employs regularization divided by initial estimators and is characterized by asymptotic normality and variable selection consistency.
Masaaki Takada, Hironori Fujisawa
openaire   +3 more sources

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Transposon sequencing reveals Burkholderia gene fitness in a spaceflight-relevant plant-pathogen interaction

Applied and Environmental Microbiology
The spaceflight environment imparts unique selective pressures on the plants and microbes of plant growth chambers on the International Space Station (ISS), which generally manifests through genetic signatures associated with a heightened response to ...
Anya Volter, Jessica Atkin, Aaron Curry, Anirudha Dixit, Rachel Tucker, Hannah Roberts, Mary Hummerick, Elison B. Blancaflor, Aubrie O'Rourke   +8 more
doaj   +1 more source