Results 91 to 100 of about 160,127 (291)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Calcite covering of sediment as a possible way of curbing blue-green algae [PDF]

, 1992
Natural calcite precipitation in lakes is a well-known control mechanism of eutrophication. In hard-water lakes, calcite deposits on the flat bottoms of shallow lakes and near the shores of deeper lakes resulted from biogenic decalcification during the ...
Klapper, H.
core  

Carbon Isotope Constraints on the Deglacial CO2 Rise from Ice Cores [PDF]

, 2012
The stable carbon isotope ratio of atmospheric CO2 (d13Catm) is a key parameter in deciphering past carbon cycle changes. Here we present d13Catm data for the past 24,000 years derived from three independent records from two Antarctic ice cores.
Chappellaz, J., Elsig, J., Fischer, Hubertus, Joos, F., Köhler, P., Leuenberger, D., Leuenberger, M., Lourantou, A., Schmitt, Jochen, Schneider, R., Stocker, T. F.   +10 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Slow Dynamics of Hydrate Systems Revealed by a Double BSR

Geophysical Research Letters
Determining how gas hydrate distribution evolved along continental margins in the past is essential to understanding its evolution in the future. Moreover, hydrate decomposition has been linked to several catastrophic events, including some of the ...
M. Fabre, V. Riboulot, L. Loncke, S. Ker, G. Ballas, Y. Thomas, G. Ion, N. Sultan   +7 more
doaj   +1 more source

Controls on interior West Antarctic Ice Sheet Elevations: inferences from geologic constraints and ice sheet modeling [PDF]

, 2013
Knowledge of the West Antarctic Ice Sheet (WAIS) response to past sea level and climate forcing is necessary to predict its response to warmer temperatures in the future.
Ackert Jr., Robert P., Borns Jr., Harold W., DeConto, Robert M., Kurz, Mark D., Mukhopadhyay, Sujoy, Pollard, David, Putnam, Aaron Ervin   +6 more
core   +2 more sources

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Pliocene and Pleistocene chronostratigraphy and paleoenvironment of the Central Arctic Ocean, using deep water agglutinated foraminifera [PDF]

, 1998
Deep-water agglutinated foraminifera (DWAF) were studied from Cores PS2177-5, PS2200-5, PS2212-3 and PS2185-6; from the R/V POLARSTERN ARK-VIII/3 Cruise in the central Arctic Ocean.
Evans, J.R., Kaminski, M.A.
core   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Landscape reconstructions for Europe during the late Last Glacial (60–20 ka BP): a pollen-based REVEALS approach [PDF]

Earth System Science Data
Vegetation change during the Last Glacial period in Europe plays a crucial role in better understanding the ecosystem dynamics response to abrupt climate change. Yet, most quantitative reconstructions of land-cover primarily focus on the Holocene and aim
O. A. Kern, A. Maier, N. Vercauteren
doaj   +1 more source