Results 101 to 110 of about 14,619,398 (348)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

FORUM: Review clarification

open access: yesPacific Journalism Review, 2004
An amendment of the Red & Green journal review that featured in the last issue of PJR (Volume 9, pp 197-200).
Geraldene Peters
doaj   +1 more source

Irregular no. 31; Apr. 1970 [PDF]

open access: yes, 1970
In this issue: 1. Good Stuff on Urban Renewal - The Committee for Urban Action circulated a second document on the bills before Parliament called "Principles for an Urban Renewal Bill". Part of this document - its introduction summarising the principles

core  

Managed Forgetting to Support Information Management and Knowledge Work

open access: yes, 2018
Trends like digital transformation even intensify the already overwhelming mass of information knowledge workers face in their daily life. To counter this, we have been investigating knowledge work and information management support measures inspired by ...
Dengel, Andreas   +6 more
core   +1 more source

Quantum-Gravity Phenomenology: Status and Prospects [PDF]

open access: yes, 2002
Over the last few years part of the quantum-gravity community has adopted a more optimistic attitude toward the possibility of finding experimental contexts providing insight on non-classical properties of spacetime.
Ahluwalia D.V.   +13 more
core   +3 more sources

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Special Issue “Targets, Tracers and Translation Novel Radiopharmaceuticals Boost Nuclear Medicine”

open access: yesPharmaceuticals, 2019
This is the fourth Special Issue in Pharmaceuticals within the last six years dealing with aspects of radiopharmaceutical sciences [...]
Gerald Reischl
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Cut Loose: State and Local Layoffs of Public Employees in the Current Recession [PDF]

open access: yes, 2009
In the current recession, millions of Americans have lost their jobs. Unemployment has increased nationwide to levels not witnessed since the 1980s. This issue brief tallies more than 110,000 jobs that have been shed from state and local governments in ...
Matt Sherman, Nathan Lane
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