Results 121 to 130 of about 14,619,398 (348)
Electronic Publishing Programs in Science and Technology Part 2: Abstracting and Indexing Services
In the last issue, we looked at electronic journals being made available over the world wide web. In this issue we survey indexing and abstracting services available over the web.
Elizabeth W. Brown, Andrea L. Duda
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Ecoso exchange newsletter : ecological, sociological and political discourse 2/42; Dec. 1996 [PDF]
This issue of Ecoso is mainly about citizenship and the labour movement. Contents: Page 1. A Charter for All Children 2. Unions and Citizenship by Peter Gibbons (AMEU) 4. Unions and Citizenship by Jenny Drabby (VTHC) 5.
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B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Five minutes with Noam Chomsky – “Europe is pretty much following behind US policy, no matter what that policy is” [PDF]
Last week the General Assembly of the United Nations voted in favour of recognising Palestine as a non-member observer state. The EU was unable to reach a common position on the issue, with some states voting in favour and others, including Germany and ...
Chomsky, Noam
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