Results 31 to 40 of about 13,477 (288)

24-Hour efficacy of single primary selective laser trabeculoplasty versus latanoprost eye drops for Naïve primary open-angle glaucoma and ocular hypertension patients

Scientific Reports, 2023
This prospective, observer-masked, randomized clinical trial was conducted between December 2018 and June 2021 at Eye Hospital, China Academy of Chinese Medical Sciences. A total of 45 glaucoma patients from Beijing, China, were enrolled in this clinical
Yipeng Shi, Yan Zhang, Wenying Sun, Alex S. Huang, Shuang Chen, Lixia Zhang, Wei Wang, Like Xie, Xiaobin Xie   +8 more
doaj   +1 more source

Sustained latanoprost release from PEGylated solid lipid nanoparticle-laden soft contact lens to treat glaucoma

Pharmaceutical development and technology (Print), 2021
Contact lens have been proposed as a mean of ocular drug delivery, but the conventional soaking method to load hydrophobic drugs, such as latanoprost shows low drug loading and high burst release with alteration in the critical lens properties.
H. Dang, Chunyun Dong, Li Zhang
semanticscholar   +1 more source

Ocular hypotensive efficacy of a new liposomal latanoprost formulation administered by different routes for experimental ocular hypertension

Journal of Ophthalmology, 2022
Background: Prostaglandin analogs (e.g., latanoprost) are the first-line therapy for glaucoma. These medications, however, have a short antihypertensive effect due to low penetration of topical drug across the corneal epithelium, which causes the need ...
I. M. Mikheytseva, G. S. Grygorieva, N. V. Pasyechnikova, S. G. Kolomiichuk, T. I. Siroshtanenko, N. F. Konakhovych   +5 more
doaj   +1 more source

A comparative study of combined microneedling and narrowband ultraviolet B phototherapy versus their combination with topical latanoprost in the treatment of vitiligo

Dermatologic Therapy, 2021
Regardless of the continuous discovery of innovative modalities for the treatment of vitiligo, none of them ensure excellent therapeutic outcome. Microneedling had been suggested either singly or concomitantly with other therapeutic modalities for ...
Y. M. Neinaa, S. Lotfy, N. R. Ghaly, N. Doghaim   +3 more
semanticscholar   +1 more source

Preservative-free versus preserved latanoprost eye drops for reducing intraocular pressure: a non-inferiority phase III randomized, multi-center, single-blind, parallel-group controlled trial [PDF]

, 2021
Background: The aim of this study was to test the non-inferiority of preservative-free (PF) latanoprost 50 μg/mL multi-dose ophthalmic solution versus the marketed benzalkonium chloride (BAK)-preserved latanoprost 50 μg/mL ophthalmic solution in ...
Dimera, Vasiliki, Georgakopoulos, Constantinos D, Halkiadakis, Ioannis, Kalantzi, Lida, Kanonidou , Evgenia, Konstas, Anastasios, Koufakis, Dimitrios, Margaritis, Antonios, Soulele, Konstantina, Theodosiadis, Panos, Zintzaras, Elias   +10 more
core   +2 more sources

Comparison of ocular surface assessment and adherence between preserved and preservative-free latanoprost in glaucoma: a parallel-grouped randomized trial

Scientific Reports, 2021
Given that nonadherence is related to subject characteristics and drug tolerance and preserved eye drops tend to be more intolerable than preservative-free ones, we conducted a phase 4, parallel-grouped, investigator-blind, active-control, randomized ...
Dai Woo Kim, J. Shin, C. Lee, Myung-Kyung Kim, Soh-Young Lee, S. Rho   +5 more
semanticscholar   +1 more source

Preserved Versus Preservative-Free Latanoprost for the Treatment of Glaucoma and Ocular Hypertension: A Post Hoc Pooled Analysis

Advances in Therapy, 2021
To compare the tolerability and efficacy of a preservative-containing latanoprost (PCL) to a preservative-free formulation of latanoprost (PFL) in patients with open-angle glaucoma or ocular hypertension. A pooled analysis was performed of data from five
P. Harasymowycz, C. Hutnik, J. Rouland, F. M. Negrete, Mario A. Economou, P. Denis, C. Baudouin   +6 more
semanticscholar   +1 more source

Intraocular Pressure Reduction Effect of 0.005% Latanoprost Eye Drops in a Hyaluronic Acid-Chitosan Nanoparticle Drug Delivery System in Albino Rabbits

Translational Vision Science & Technology, 2021
Purpose The purpose of this study was to evaluate the intraocular pressure (IOP) reduction efficiency of hyaluronic acid-chitosan-latanoprost link nanoparticle (HA-CS-latanoprost link NP) formulated eye drops.
Ana Marie L. Rubenicia, L. Cubillan, V. Sicam, A. Macabeo, Oliver B. Villaflores, Agnes L Castillo   +5 more
semanticscholar   +1 more source

A comparative evaluation of the efficacy and safety of Latanoprost-Optic and Xalatan used as monotherapy and combined with Dorzolamide-Optic for primary open-angle glaucoma under clinical practice conditions

Российский офтальмологический журнал, 2023
The number of ophthalmic antihypertensive drugs available in Russia is steadily increasing, which complicates the choice to be made by ophthalmologist practitioners.
D. P. Novikov, O. A. Frolov, A. S. Pokrovsky, V. V. Novikova   +3 more
doaj   +1 more source

A randomized comparative study of the efficacy of topical latanoprost versus topical betamethasone diproprionate lotion in the treatment of localized alopecia areata.

Indian Journal of Dermatology, Venereology and Leprology, 2021
BACKGROUND Topical corticosteroids are the standard therapy for the treatment of alopecia areata. Recently, topical latanoprost has been found effective in the treatment of eyelash alopecia areata.
Sonal Bhat, S. Handa, D. De
semanticscholar   +1 more source