Comparative Effectiveness of Timolol-Based Fixed-Combination Regimens for Glaucoma: a Retrospective Cohort Study Using Target Trial Emulation Framework [PDF]
Ophthalmology and TherapyIntroduction Glaucoma is a leading cause of irreversible blindness, and many patients ultimately require escalation beyond monotherapy to maintain adequate intraocular pressure control.
Chin Lai +5 more
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National Journal of Physiology, Pharmacy and Pharmacology, 2022 Background: Studies comparing the efficacy and tolerability of the three fixed combinations of timolol with its monotherapy are not readily available. In this background, the current prospective observational study was planned.
Dibyendu Chakraborty +2 more
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Comparison of the efficacy and safety of fixed combination travoprost/timolol and dorzolamide/timolol in patients with primary open-angle glaucoma and ocular hypertension [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2013 Introduction. Combining two medications in one bottle may improve compliance by reducing the time required to administer drops and the frequency of the total number of medication bottles. Objective.
Babić Nikola +4 more
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Antioxidant activity of dorzolamide/timolol fixed combination in neuroprotective therapy in glaucoma
Oftalʹmologiâ, 2014 Purpose: to study the antioxidant activity of carbonic anhydrase inhibitors and timolol fixed combinations and to compare it with other fixed combinations.Methods: Antioxidant activity (AOA) of dorzolamide/timolol (Cosopt), dorzolamide/timolol (Dorzopt ...
N. I. Kurysheva +2 more
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A Randomized, Double-Blinded, Placebo-Controlled, Cross Over Study Evaluating the Efficacy and Safety of Timolol Ophthalmic Solution as an Acute Treatment of Migraine [PDF]
, 2020 Introduction. Daily oral beta-adrenoreceptor antagonist has been shown to be effective in preventing migraine headaches. Timolol 0.5% ophthalmic solution is a non-selective beta-adrenoreceptor antago- nist, where the primary use is for glaucoma.
Aggarwal, Dipika +10 more
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Intraocular pressure-lowering effects of commonly used fixed combination drugs with timolol in the management of primary open angle glaucoma [PDF]
International Journal of Ophthalmology, 2014 AIM:To evaluate intraocular pressure (IOP)-lowering effect and ocular tolerability of brimonidine/timolol, dorzolamide/timolol and latanoprost/timolol fixed combination therapies in the management of primary open angle glaucoma.METHODS:Each drug was ...
Murat Atabey Ozer +2 more
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Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis. [PDF]
, 2005 BACKGROUND: Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown.
Bosch, J +12 more
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PLoS ONE, 2012 BackgroundThe first goal of medical therapy in glaucoma is to reduce intraocular pressure (IOP), and the fixed-combination medications are needed to achieve sufficiently low target IOP.
Jin-Wei Cheng +4 more
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Pharmacogenetics of ophthalmic topical β-blockers [PDF]
, 2008 Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
McCarty, Catherine A. +4 more
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The parallel lives of polysaccharides in food and pharmaceutical formulations [PDF]
, 2015 The present opinion article discusses how polysaccharide structures can be used in both food and pharmaceutical formulations. We distinguish two regions depending on moisture content where polysaccharides form structures with distinct functional ...
Kontogiorgos, Vassilis +2 more
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