Results 21 to 30 of about 720 (121)

A comparative study on the efficacy and cost-effectiveness of latanoprost and timolol in glaucoma

National Journal of Physiology, Pharmacy and Pharmacology, 2020
Background: Glaucoma is a chronic, progressive optic neuropathy which leads to optic nerve damage and loss of visual function. Elevated intraocular pressure (IOP) is the most important and only modifiable risk factor.
Iram Shaifali, Neetu Gupta, Shalini Chandra, Kanupriya Agarwal   +3 more
doaj   +1 more source

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Two Stability Indicating Chromatographic Methods: TLC Densitometric versus HPLC Method for the Simultaneous Determination of Brinzolamide and Timolol Maleate in Ophthalmic Formulation in the Presence of Probable Carcinogenic Oxidative Degradation Product of Timolol Maleate

Separations, 2023
A comparative study between two stability-indicating chromatographic methods for the assay of brinzolamide and timolol maleate in the co-existence of the probable carcinogenic oxidative degradation product of timolol maleate in their ophthalmic ...
Asmaa A. Mandour, Nada Nabil, Hala E. Zaazaa, Munjed M. Ibrahim, Mohamed A. Ibrahim   +4 more
doaj   +1 more source

Early Intervention Effects and Risk Factors for Residual Skin Changes in Infantile Hemangiomas

The Journal of Dermatology, EarlyView.
ABSTRACT Infantile hemangioma (IH) characteristically progresses through proliferative, involuting, and involuted phases, and typically undergoes spontaneous regression after the age of five. Therefore, the traditional management strategy has been based on a “wait‐and‐see policy”.
Kayoko Okuda, Motoki Nakamura, Reiko Nakamura, Sachiyo Takagi, Akimichi Morita   +4 more
wiley   +1 more source

Long-term cost and efficacy analysis of latanoprost versus timolol in glaucoma patients in Germany

International Journal of Ophthalmology, 2013
AIM: To evaluate 5-year effectiveness and cost between latanoprost or timolol monotherapy in a pilot trial. METHODS: A retrospective, multi-center trial performed at 6 sites in Germany of patients who had a diagnosis of primary open-angle or ...
Jeanette A. Stewart, Lindsay A. Nelson, Michael S. Kristoffersen, Sonja Schölzel, Dietmar Schnober, Ulrich Thelen, William C. Stewart   +6 more
doaj   +1 more source

Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas

Pharmaceutics, 2022
Infantile hemangiomas (IH) leave sequelae after involution. Topical application of timolol maleate (TM) is the mainstream treatment for superficial lesions but is limited by its low penetrable properties.
Shih-Jen Chang, Huiyuan Wang, Jialin Chen, Qianyi Chen, Lei Chang, Yongzhuo Huang, Yajing Qiu, Xiaoxi Lin   +7 more
doaj   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Efikasi Terapi Topikal Kortikosteroid Ultrapoten, Solusio, dan Gel Timolol Maleat 0,5% Terhadap Hemangioma Infantil Superfisial

Sari Pediatri, 2016
Latar belakang. Terapi kortikosteroid ultrapoten menjadi terapi topikal standar untuk HI. Namun, kortikosteroid banyak efek samping dan respon yang kadang gagal, perlu alternatif terapi topikal lain.
Lukman Ariwibowo, Arief Budiyanto, Retno Danarti   +2 more
doaj   +1 more source

Traction suture fixation technique using a capsular tension ring fragment for severe lens displacement during cataract surgery in dogs

Veterinary Ophthalmology, Volume 28, Issue 2, Page 197-206, March 2025.
Abstract Objectives To describe the traction suture fixation technique for severely displaced lenses (≥180°) using a capsular tension ring (CTR) fragment during cataract surgery in dogs, and to retrospectively investigate its clinical outcomes. Animals Studied Eight dogs (nine eyes). Procedures The medical records of dogs with severe lens displacement (
Shinya Fukumoto, Tomomi Minamoto
wiley   +1 more source