Results 41 to 50 of about 720 (121)

Development of an Efficient and Scalable Process for Preparing Timolol N‐Nitrosamine Impurities B, C, E, H, I, J, and Their ADMET Evaluation

Journal of Heterocyclic Chemistry, Volume 63, Issue 7, Page 1099-1113, July 2026.
N‐nitrosamine impurities (B, C, E, H, I, J) of timolol maleate are easily synthesized from diethyl malonate and 3,4‐dichloro‐1,2,5‐thiadiazole. Good yields and precise impurity profiling are made possible by the effective technique, which also ensures pharmaceutical safety and strengthens regulatory compliance.
Kottolla Sai Prasad, Chithaluri Sudhakar, Vijaya Krishna Ravi, Bijaya Kethan Sahoo   +3 more
wiley   +1 more source

Timolol maleate 0.5% versus timolol maleate in gel forming solution 0.5% (timolol GFS) in open angle glaucoma in India. Preliminary safety and efficacy study

Indian Journal of Ophthalmology, 2002
Purpose: To compare the efficacy and safety profile of Timolol maleate 0.5% versus Timolol gel forming solution (GFS) 0.5% in open angle glaucoma in Indian eyes.Methods: In a prospective crossover study 52 patients of open angle glaucoma ...
Kumar Harsh, Sudan Rajeev, Sethi Harinder, Sony Parul   +3 more
doaj  

Association between Ophthalmic Timolol and Hospitalisation for Bradycardia

Journal of Ophthalmology, 2015
Introduction. Ophthalmic timolol, a topical nonselective beta-blocker, has the potential to be absorbed systemically which may cause adverse cardiovascular effects.
Nicole L. Pratt, Emmae N. Ramsay, Lisa M. Kalisch Ellett, Tuan A. Nguyen, Elizabeth E. Roughead   +4 more
doaj   +1 more source

Direct Inhibition of N-Methyl-D-Aspartate (NMDA)-Receptor Function by Antiglaucomatous β-Antagonists

Journal of Pharmacological Sciences, 2008
In the present study, we investigated the direct effects of antiglaucoma drugs (timolol, betaxolol, pilocarpine, and latanoprost) on N-methyl-D-aspartate (NMDA)-receptor function using a Xenopus oocytes expression system and electrophysiological ...
Tatsuo Nagata, Susumu Ueno, Hirofumi Morita, Toshiaki Kubota, Yumiko Toyohira, Masato Tsutsui, Akihiko Tawara, Nobuyuki Yanagihara   +7 more
doaj   +1 more source

Global scope of glaucoma clinical practice for optometrists

Optometry and Vision Science, Volume 103, Issue 7, July 2026.
ABSTRACT Purpose The role of optometrists in glaucoma care is evolving rapidly in many parts of the world. This review aims to describe the current global scope of clinical practice for optometrists with respect to glaucoma, highlighting progress and identifying barriers to care across diverse regions.
Jonathan Denniss, Brendan T. Barrett, Riccardo Cheloni, Patrick J. G. Gunn, Robert A. Harper, Sarah MacIver, Allison M. McKendrick, Stephen Ocansey, Philip R. K. Turnbull, John G. Flanagan   +9 more
wiley   +1 more source

Efficacy and safety of travoprost/timolol vs dorzolamide/timolol in patients with open-angle glaucoma or ocular hypertension

Clinical Ophthalmology, 2009
Miguel A Teus1, Stefano Miglior2, Guna Laganovska3, Lasma Volksone4, Bozena Romanowska-Dixon5, Roman Gos6, Gábor Holló7, for the C-05-25 Study Group81Hospital Príncipe de Astúrias, Universidad de Alcal& ...
Miguel A Teus, Stefano Miglior, Guna Laganovska, et al   +3 more
doaj  

Two Cases of Fibrin Membrane‐Induced Pupillary Block Treated With Neodymium‐Doped Yttrium Aluminium Garnet (Nd:YAG) Laser After Cataract Surgery in Dogs

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study evaluates the clinical efficacy of Nd:YAG laser membranotomy in dogs with fibrin membrane‐induced pupillary block (FMPB). Targeted application of the Nd:YAG laser safely disrupts the obstructive pupillary membrane, thereby restoring normal aqueous humour outflow and effectively resolving secondary intraocular pressure (IOP) elevation without
Haerin Yoon, Jiyi Hwang, Ji Seung Jung, Myeon‐Jee Kwon, Jungyeon Yong, Sungin Lee, Kyung‐Mee Park   +6 more
wiley   +1 more source

Effectiveness of galcanezumab versus topiramate, amitriptyline, and other select traditional oral migraine preventives with evidence of efficacy: 3‐Month results from the TRIUMPH study

Headache: The Journal of Head and Face Pain, Volume 66, Issue 7, Page 1525-1536, July/August 2026.
Abstract Objective To compare the 3‐month effectiveness of galcanezumab with select traditional oral migraine preventive (TOMP) medications recommended by scientific societies (TOMP efficacy subset) and with the most frequently used individual TOMP medications.
Shivang Joshi, Cristina Tassorelli, Manjit Matharu, Taoufik Alsaadi, Carlos Vallarino, Lars Viktrup, Maurice Vincent, Rebecca L. Robinson   +7 more
wiley   +1 more source

Effects of Latanoprost 0.005%/Timolol Maleate 0.5% and Dorzolamide 2%/Timolol Maleate 0.5% Fixed Combinations on 24-hour Intraocular Pressure in Patients with Primary Open-Angle Glaucoma

Türk Oftalmoloji Dergisi, 2012
Pur po se: To evaluate the effects of latanoprost/timolol maleate and dorzolamid/timolol maleate fixed combinations on-24 hours intraocular pressure in patients with open-angle glaucoma.
Berna Yüce, Suzan Güven Yılmaz, Kutay Andaç, Halil Ateş   +3 more
doaj   +1 more source

A study on the treatment of infantile hemangiomas with topical timolol

Indian Journal of Paediatric Dermatology, 2020
Introduction: With the advent of topical timolol, there has been a tremendous change in the management of infantile hemangiomas. Aims: The aim of the study was to evaluate the treatment response with topical 0.5% timolol drops in 20 children of infantile
Neerja Puri
doaj   +1 more source