Results 71 to 80 of about 47,514 (302)

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Evidence of Rocky Planetesimals Orbiting Two Hyades Stars

, 2013
The Hyades is the nearest open cluster, relatively young and containing numerous A-type stars; its known age, distance, and metallicity make it an ideal site to study planetary systems around 2-3 Msun stars at an epoch similar to the late heavy ...
Farihi, J., Gänsicke, B. T., Koester, D.   +2 more
core   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma, Huan Deng, Zelin Liu, Simei Zhong, Liangliang Wang, Mu He, Ning Jing, Lihua Dai, Yuzhen Basang, Xiao‐Yu Hu, Changyi Zhang, Huimin Zeng, Haoren Shao, Zhe Yang, Shanshan Zhao, Xiaohai Hu, Chuanjie Zhang, Xiaowei Wu, Jing Xu, Shaoqun Zeng, Jing Yuan, Qiang Li, Ziwei Qu, Zhenya Hong, Lingjuan Chen, Hanhua Dong, Jia Guo, Zhiqiang Han, Yu‐Hui Zhang   +28 more
wiley   +1 more source

The Mass Dependence of Hα Emission and Stellar Spindown for Fully Convective M Dwarfs

The Astrophysical Journal
Fully convective M dwarfs typically remain rapidly rotating and magnetically active for billions of years, followed by an abrupt and mass-dependent transition to slow rotation and quiescence.
Emily K. Pass, David Charbonneau, David W. Latham, Perry Berlind, Michael L. Calkins, Gilbert A. Esquerdo, Jessica Mink   +6 more
doaj   +1 more source

The Progenitors of Dwarf Spheroidal Galaxies [PDF]

, 2003
Dwarf spheroidal (dSph) galaxies present an evolutionary puzzle that we explore in 40 early- and late-type dwarfs in the Local Group and nearby field.
Bonifacio P., Carignan C., Daniel Harbeck, Davies J. I., de Boer K. S., Eskridge P. B., Eva K. Grebel, Grebel E. K., Hirashita H., Hirashita H., John S. Gallagher III, Karachentsev I., Koribalski B., Oort J. H., Phillipps S., Richer M., Skillman E. D., Tolstoy E.   +17 more
core   +3 more sources

Comparative Insights and Overlooked Factors of Interphase Chemistry in Alkali Metal‐Ion Batteries

Advanced Energy Materials, EarlyView.
This review presents a comparative analysis of Li‐, Na‐, and K‐ion batteries, focusing on the critical role of electrode–electrolyte interphases. It especially highlights overlooked aspects such as SEI/CEI misconceptions, binder effects, and self‐discharge relevance, emphasizing the limitations of current understanding and offering strategies for ...
Changhee Lee, Zachary T. Gossage, Shinichi Kumakura, Shinichi Komaba   +3 more
wiley   +1 more source

The Influence of Chromospheric Activity on Line Formation

The Astrophysical Journal
One of the primary sources of stellar spectral variability is magnetic activity. While our current understanding of chromospheric activity is largely derived from specific lines sensitive to chromospheric heating, such as the Ca ii H and K doublet ...
Mariela C. Vieytes, Lily L. Zhao, Megan Bedell   +2 more
doaj   +1 more source

Bayesian Optimization Guiding the Experimental Mapping of the Pareto Front of Mechanical and Flame‐Retardant Properties in Polyamide Nanocomposites

Advanced Intelligent Discovery, EarlyView.
Bayesian optimization enabled the design of PA56 system with just 8 wt% additives, achieving limiting oxygen index 30.5%, tensile strength 80.9 MPa, and UL‐94 V‐0 rating. Without prior knowledge, the algorithm uncovered synergistic effects between aluminum diethyl‐phosphinate and nanoclay.
Burcu Ozdemir, Miguel Hernández‐del‐Valle, Christina Schenk, De‐Yi Wang, Maciej Haranczyk   +4 more
wiley   +1 more source

Analysis of Six Long-period Low-mass Eclipsing Binaries

The Astronomical Journal
The radius inflation is predominantly observed in short-period, low-mass stellar systems, while being rarely detected in long-period binaries. Using Transiting Exoplanet Survey Satellite photometric and Large Sky Area Multi-Object Fiber Spectroscopic ...
Yang Pan, Antonio Frasca, Jiaxin Wang, Jianning Fu, Xiaobin Zhang   +4 more
doaj   +1 more source