Results 101 to 110 of about 8,510,179 (297)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Astrophysical JournalWe examine the spatial distributions of luminous blue variables (LBVs), B [ e ] supergiants, and Wolf–Rayet stars (WR) stars in the Large Magellanic Cloud (LMC) to clarify their relative ages, evolutionary states, and relationships. This survey employs a
John C. Martin +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The SN 2023ixf Progenitor in M101. II. Properties
The Astrophysical JournalWe follow our first paper with an analysis of the ensemble of the extensive preexplosion ground- and space-based infrared observations of the red supergiant (RSG) progenitor candidate for the nearby core-collapse supernova SN 2023ixf in Messier 101 ...
Schuyler D. Van Dyk +14 more
doaj +1 more source
The formation radius of HCN in O-rich asymptotic giant branch stars
Astronomy & AstrophysicsContext. Molecules detected in circumstellar envelopes around asymptotic giant branch (AGB) stars are generally well explained in terms of formation under chemical equilibrium in the stellar atmosphere or photochemistry in the outer expanding layers ...
Marinho L. +5 more
doaj +1 more source
Neutral Oxygen in Late-Type Stars
The Astrophysical Journal, 1967 We have identified the forbidden absorption nebular and auroral lines of oxygen in the spectra of about seventy G and K stars, mostly giants. While weak, they appear in a relatively uncrowded spectral region and can be studied at high dispersion.
Peter S. Conti +4 more
openaire +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Magnetic fields in A stars besides Ap stars
, 2014 I review ongoing efforts to understand the incidence of magnetism in intermediate-mass stars that are different from the magnetic Ap stars. This includes the search for magnetic fields in chemically peculiar stars of the Am and HgMn types as well as in ...
Kochukhov, Oleg,
core
Carbon Stars from Gaia Data Release 3 and the Space Density of Dwarf Carbon Stars
The Astrophysical JournalCarbon stars (with atmospheric C/O > 1) range widely in temperature and luminosity, from low-mass dwarfs to asymptotic giant branch (AGB) stars. The main-sequence dwarf carbon (dC) stars have inherited carbon-rich material from an AGB companion, which ...
Benjamin R. Roulston +3 more
doaj +1 more source