Results 111 to 120 of about 440,001 (300)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

OH spectral evolution of oxygen-rich late-type stars

, 2004
We investigated the main-line spectral evolution with shell thickness of oxygen rich AGB stars. The study is based on a sample of 30 sources distributed along the IRAS colour-colour diagram.
A. M. Le Squeren, Alcock, Bains, Baud, Baud, Bedijn, Bowers, Bowers, Chapman, Chapman, Chapman, Collison, Cook, Cooke, David, David, Deguchi, Diamond, Dickinson, Dickinson, Epchtein, Etoka, Etoka, Etoka, Field, Field, Fix, Goldreich, Habing, Huggins, Lanes, Le Squeren, Le Squeren, Lewis, Likkel, Lépine, Olnon, Reid, Richards, S. Etoka, Sivagnanam, Sivagnanam, Sun, Szymczak, Szymczak, Szymczak, Te Lintel Hekkert, Ukita, van der Veen, van der Veen, Vassiliadis, Volk, Welty, Yates, Zijlstra, Zijlstra   +55 more
core   +3 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Mapping the Outer Edge of the Young Stellar Cluster in the Galactic Center

, 2015
We present new near-infrared spectroscopic observations of the outer edges of the young stellar cluster around the supermassive black hole at the Galactic center.
Do, Tuan, Ghez, Andrea M., Lu, Jessica R., Murray, Norm, Støstad, Morten N., Yelda, Sylvana   +5 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Analysis of Six Long-period Low-mass Eclipsing Binaries

The Astronomical Journal
The radius inflation is predominantly observed in short-period, low-mass stellar systems, while being rarely detected in long-period binaries. Using Transiting Exoplanet Survey Satellite photometric and Large Sky Area Multi-Object Fiber Spectroscopic ...
Yang Pan, Antonio Frasca, Jiaxin Wang, Jianning Fu, Xiaobin Zhang   +4 more
doaj   +1 more source

Rotational evolution of slow–rotator sequence stars

Astronomy & Astrophysics
In recent years, ground- and space-based photometric surveys have characterized the rotational evolution of solar-like stars to an unprecedented level of detail.
Spada F., Lanzafame A. C.
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

X-ray spectroscopy of late-type stars [PDF]

The solid state spectrometer on the Einstein Observatory determined .4 - 4.5 keV spectra for Capella, Algol and 6 RS CVn binaries. All show evidence for a bimodal distribution of emission measure with temperature with one component approximately 7 ...
Swank, J. H., White, N. E.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source