Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source
Late Glacial and Early Holocene human demographic responses to climatic and environmental change in Atlantic Iberia. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2021 McLaughlin TR +4 more
europepmc +1 more source
High Lability Fe Particles Sourced From Glacial Erosion Can Meet Previously Unaccounted Biological Demand: Heard Island, Southern Ocean [PDF]
, 2019 Pier van der Merwe +7 more
openalex +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
South Asian monsoon history over the past 60 kyr recorded by radiogenic isotopes and clay mineral assemblages in the Andaman Sea [PDF]
, 2015 The Late Quaternary variability of the South Asian (or Indian) monsoon has been linked with glacial‐interglacial and millennial scale climatic changes but past rainfall intensity in the river catchments draining into the Andaman Sea remains poorly ...
Ali, Sajid +8 more
core +1 more source
LATE-GLACIAL STRATIGRAPHY IN ESTONIA [PDF]
Proceedings of the Estonian Academy of Sciences. Geology, 1996 Reet Pirrus, Anto Raukas
openaire +1 more source
Arthritis Care &Research, EarlyView.Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead +4 more
wiley +1 more source
LGM and Late Glacial glacier advances in the Cordillera Real and Cochabamba (Bolivia) deduced from 10Be surface exposure dating [PDF]
Climate of the Past, 2007 Surface exposure dating (SED) is an innovative tool already being widely applied for moraine dating and for Late Quaternary glacier and climate reconstruction.
H. Veit, P. W. Kubik, Ch. Kull, R. Zech
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