Results 211 to 220 of about 1,748,641 (295)

Latitudinal manganese gradient dynamics associated with Earth's major ice ages. [PDF]

Nat Commun
Wang X, Pohl A, Rickaby REM, Lu Z.
europepmc   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

The first Boreal Sable (Martes zibellina, L., 1758) in the Pleistocene Arctic Siberia. [PDF]

PLoS One
Boeskorov GG, Chlachula J, Klimovskiy AI, van der Plicht J, Protopopov AV.   +4 more
europepmc   +1 more source

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

Viral modulation of sulfur-oxidizing bacteria drives organic carbon sink formation during primary succession in deglaciating ecosystems. [PDF]

Nat Commun
Liao H, Cui HX, Chen LX, Duan CS, Li J, Zhao S, Zhu YG, Su JQ.   +7 more
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

The Biodiversity of Retreating Glaciers Leaves an Ecological Legacy in Emerging Soil Communities. [PDF]

Glob Chang Biol
Cantera I, Marta S, Carteron A, Guerrieri A, Giachello S, Bonin A, Ambrosini R, Azzoni RS, Caccianiga M, Pittino F, Simonicini A, Valle B, Gobbi M, Ficetola GF.   +13 more
europepmc   +1 more source

Iron‐Mediated Release of Aged Dissolved Organic Carbon From Waterlogged Peatland Under Warming

Advanced Science, EarlyView.
This study conducts a five‐year in situ warming experiment in high‐altitude peatlands to examine dissolved organic carbon (DOC) release. The study shows that warming promotes the release of plant‐derived modern DOC in drained peatlands, but amplifies aquatic export of century‐old DOC from waterlogged peatlands via Fe‐mediated DOC mobilization—a ...
Guohua Dai, Zhiying Yang, Zongguang Liu, Wanjia Hu, Lixiao Ma, Enze Kang, Wanqing Luo, Yunpeng Zhao, Chengzhu Liu, Juan Jia, Ting Liu, Chen He, Quan Shi, Jianliang Liu, Yongheng Gao, Huai Chen, Hailong Zhang, Meixun Zhao, Xiaojuan Feng   +18 more
wiley   +1 more source

Reply to McDannell et al.: Thermal overprinting does not obscure the tectonic origin of the Great Unconformity. [PDF]

Proc Natl Acad Sci U S A
Duan L, Christie-Blick N, Zattin M, Zhan RR, Yang Z, Wan B, Olivetti V, Zhang X.   +7 more
europepmc   +1 more source

Validation of climate model-inferred regional temperature change for late-glacial Europe. [PDF]

Nat Commun, 2014
Heiri O, Brooks SJ, Renssen H, Bedford A, Hazekamp M, Ilyashuk B, Jeffers ES, Lang B, Kirilova E, Kuiper S, Millet L, Samartin S, Toth M, Verbruggen F, Watson JE, van Asch N, Lammertsma E, Amon L, Birks HH, Birks HJ, Mortensen MF, Hoek WZ, Magyari E, Muñoz Sobrino C, Seppä H, Tinner W, Tonkov S, Veski S, Lotter AF.   +28 more
europepmc   +1 more source