Results 91 to 100 of about 1,282,772 (281)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Late bedtime was associated with increased androgen and reduced lean mass in women with polycystic ovary syndrome: a cross-sectional study

Journal of Ovarian Research
Background While the specific effects of bedtime on androgen levels and lean muscle mass remain understudied, circadian misalignment and sleep disturbances have been well-established as risk factors for various metabolic disorders.
Yuqin Zhang, Min Zhang, Meili Cai, Xiaowen Shao, Diliqingna Dilimulati, Jiayi Lu, Cuiling Zhu, Haibing Chen, Changbin Li, Shen Qu, Manna Zhang   +10 more
doaj   +1 more source

Life in the late Intermediate Period at Armatambo, Peru [PDF]

, 2018
Title from PDF of title page (University of Missouri--Columbia, viewed on October 18, 2012). ; The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. ; Dissertation advisors: Dr. Robert A. Benfer and Dr. Deborah M. Pearsall ; Vita.
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Intensity modulated radiotherapy (IMRT) or conformational radiotherapy (3D-CRT) with conventional fractionation for prostate cancer: Is there any clinical difference? [PDF]

International Brazilian Journal of Urology
Purpose: To compare the treatment outcomes of a cohort of prostate cancer patients treated with conventional schedule using IMRT or 3DRT technique.
Gustavo Viani, Ana Carolina Hamamura, Alexandre C. Faustino   +2 more
doaj   +2 more sources

Persistence, Poisoning, and Autocorrelations in Dilute Coarsening

, 1997
We calculate the exact autocorrelation exponent lambda and persistence exponent theta, and also amplitudes, in the dilute limit of phase ordering for dimensions d >= 2.
Lee, Benjamin P., Rutenberg, Andrew D.
core   +1 more source

Deriving reaction mechanisms from kinetic spectroscopy. Application to late rhodopsin intermediates

Biophysical Journal, 1997
A general algebraic approach to the kinetic analysis of time-dependent absorption data is presented that allows the calculation of possible kinetic schemes. The kinetic matrices of all possible reaction mechanisms are calculated from experimental eigenvalues and eigenvectors derived from the decay constants and amplitude spectra (b-spectra) of the ...
Szundi, I., Lewis, J.W., Kliger, D.S.
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Late Quaternary changes in Mediterranean intermediate water density and formation rate

Paleoceanography, 1989
Three recently acquired eastern Mediterranean cores containing Late Quaternary sediments display a marked faunal contrast between the Holocene and older sapropels. It is suggested that the absence of neogloboquadrinids in the Holocene sapropel and their abundance in older sapropels reflect differences in food availability related to the extent of ...
Rohling, Eelco J., Gieskes, Winfried W. C.   +1 more
openaire   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source