Results 91 to 100 of about 1,274,726 (282)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Life in the late Intermediate Period at Armatambo, Peru [PDF]

open access: yes, 2018
Title from PDF of title page (University of Missouri--Columbia, viewed on October 18, 2012). ; The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. ; Dissertation advisors: Dr. Robert A. Benfer and Dr. Deborah M. Pearsall ; Vita.
openaire   +2 more sources

Late bedtime was associated with increased androgen and reduced lean mass in women with polycystic ovary syndrome: a cross-sectional study

open access: yesJournal of Ovarian Research
Background While the specific effects of bedtime on androgen levels and lean muscle mass remain understudied, circadian misalignment and sleep disturbances have been well-established as risk factors for various metabolic disorders.
Yuqin Zhang   +10 more
doaj   +1 more source

Persistence, Poisoning, and Autocorrelations in Dilute Coarsening

open access: yes, 1997
We calculate the exact autocorrelation exponent lambda and persistence exponent theta, and also amplitudes, in the dilute limit of phase ordering for dimensions d >= 2.
Lee, Benjamin P., Rutenberg, Andrew D.
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Deriving reaction mechanisms from kinetic spectroscopy. Application to late rhodopsin intermediates

open access: yesBiophysical Journal, 1997
A general algebraic approach to the kinetic analysis of time-dependent absorption data is presented that allows the calculation of possible kinetic schemes. The kinetic matrices of all possible reaction mechanisms are calculated from experimental eigenvalues and eigenvectors derived from the decay constants and amplitude spectra (b-spectra) of the ...
Szundi, I., Lewis, J.W., Kliger, D.S.
openaire   +2 more sources

Intensity modulated radiotherapy (IMRT) or conformational radiotherapy (3D-CRT) with conventional fractionation for prostate cancer: Is there any clinical difference? [PDF]

open access: yesInternational Brazilian Journal of Urology
Purpose: To compare the treatment outcomes of a cohort of prostate cancer patients treated with conventional schedule using IMRT or 3DRT technique.
Gustavo Viani   +2 more
doaj   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Late Quaternary changes in Mediterranean intermediate water density and formation rate

open access: yesPaleoceanography, 1989
Three recently acquired eastern Mediterranean cores containing Late Quaternary sediments display a marked faunal contrast between the Holocene and older sapropels. It is suggested that the absence of neogloboquadrinids in the Holocene sapropel and their abundance in older sapropels reflect differences in food availability related to the extent of ...
Rohling, Eelco J.   +1 more
openaire   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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