Results 101 to 110 of about 2,746,446 (292)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Late postoperative stenosis of the intermediate bile duct
, 1975 Se presentan 3 observaciones de estenosis tardía de la via biliar extrahepática intermedia, consecutivas a operaciones en las cuales la continuidad de la vía biliar no fue interrumpida. Las manifestaciones clínicas aparecidas tardíamente, sugirieron cuadros completamente diferentes a los hallados en el acto operatorio; Todas se trataronde estenosis ...
Bergalli, Luis E. +6 more
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
, 1997 Negli anni 1997-1998 sono stato dipendente del Fermi National Accelerator Laboratory e ho contruito alla progettazione e costruzione del rivelatore successivamente installato nell'esperimento CDF per la presa dati "Run II" del Tevatron degli anni 2001 ...
DONATI, SIMONE +1 more
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Rankings of Income Distributions: A Note on Intermediate Inequality Indices [PDF]
The purpose of this paper is to analyze the advantages and disadvantages of several intermediate inequality measures, paying special attention to whether inequality rankings between income distributions are affected by the monetary units in which incomes
Coral del Río, Olga Alonso-Villar
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
International Quota Transfer and Intermediate Goods [PDF]
In this paper we use a general equilibrium model to examine the effects of international quota transfer when a quota restricts world commodity production whilst the trade in an intermediate good is not regulated.
Aldanondo, Ana Maria, Puertolas, Javier
core
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source