Results 91 to 100 of about 2,746,446 (292)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Intermediate a mejoramiento exam v4
Written exam for students who have completed Units 7 to 12 of the Face2Face Pre-Intermediate Student´s Book and Units 1 to 3 of the Face2Face Intermediate Student´s Book published by Cambridge University ...
Pedley, Emma
core
Intensity modulated radiotherapy (IMRT) or conformational radiotherapy (3D-CRT) with conventional fractionation for prostate cancer: Is there any clinical difference? [PDF]
Purpose: To compare the treatment outcomes of a cohort of prostate cancer patients treated with conventional schedule using IMRT or 3DRT technique.
Gustavo Viani +2 more
doaj +2 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Intermediate a mejoramiento exam v5
Written exam for students who have completed Units 7 to 12 of the Face2Face Pre-Intermediate Student´s Book and Units 1 to 3 of the Face2Face Intermediate Student´s Book published by Cambridge University ...
Pedley, Emma
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Development Accounting with Intermediate Goods [PDF]
Do intermediate goods help explain relative and aggregate productivity differences across countries? Three observations suggest they do: (i) intermediates are relatively expensive in poor countries; (ii) goods industries demand intermediates more ...
Jan Grobovšek
core
Jack Frederick Kilpatrick, Oklahoma's Cherokee Composer: An Analysis of Six Intermediate Collections for Solo Piano [PDF]
Jack Frederick Kilpatrick (1915 – 1967) was the first Cherokee to receive widespread acclaim as a composer. Born in Stilwell, OK, Kilpatrick learned music at an early age and earned music degrees from the University of Redlands and American Catholic ...
Coie, Hayden
core
Del Horizonte Medio al Horizonte Tardío en la costa sur central: el caso del valle de Asia
The Asia valley, which is situated 100 km south of Lima, played an important role during the Middle Horizon. In fact, the funerary contexts of the Huaca Malena, as well as the elaborate textiles that were found in them, suggest a strong relationship with
Rommel Angeles Falcón +1 more
doaj +1 more source

