Expression Profiling of the Intermediate and Late Stages of Poxvirus Replication [PDF]
ABSTRACT The double-stranded DNA genome of vaccinia virus (VACV), the prototype poxvirus, contains approximately 200 open reading frames (ORFs) that are transcribed at early, intermediate, and late stages of infection. Previous high-throughput deep RNA sequencing allowed us to map 118 VACV early genes that are expressed before ...
Zhilong, Yang +5 more
openaire +3 more sources
Late-onset Huntington disease with intermediate CAG repeats: true or false? [PDF]
Huntington disease (HD) is a neurodegenerative disorder associated with an expanded CAG trinucleotide repeat length in the huntingtin gene. 'Intermediate alleles' with 27 to 35 CAG repeats generally do not cause HD but are unstable upon germ-line transmission.
Groen, J.L. +5 more
openaire +5 more sources
During the third and fourth epochs of the Middle Horizon, the sanctuary of Pachacamac began to have regional prestige that later increased in the Late Intermediate Period and Late Horizon.
Jesús A. Ramos Giraldo +1 more
doaj +1 more source
Resolving Late-Stage Intermediates of Eukaryotic Ribosome Assembly [PDF]
The assembly of eukaryotic ribosomes requires about 200 assembly factors promoting RNA modification, folding, cleavage, and ribosomal protein association. In this issue of Structure, Johnson et al. (2017) report structures of several late-stage intermediates of pre-40S ribosomal subunit assembly.
Erik W, Hartwick, Brian T, Wimberly
openaire +2 more sources
Drosophila S2 cells are non-permissive for vaccinia virus DNA replication following entry via low pH-dependent endocytosis and early transcription. [PDF]
Vaccinia virus (VACV), a member of the chordopox subfamily of the Poxviridae, abortively infects insect cells. We have investigated VACV infection of Drosophila S2 cells, which are useful for protein expression and genome-wide RNAi screening. Biochemical
Zain Bengali +5 more
doaj +1 more source
The human adenovirus 5 L4 promoter is activated by cellular stress response protein p53 [PDF]
During adenovirus infection, the emphasis of gene expression switches from early genes to late genes in a highly regulated manner. Two gene products, L4-22K and L4-33K, contribute to this switch by activating the Major Late Transcription Unit (MLTU) and ...
Leppard, Keith, Wright, Jordan
core +1 more source
Processing empty categories in a second language: When naturalistic exposure fills the (intermediate) gap [PDF]
An ongoing debate on second language (L2) processing revolves around whether or not L2 learners process syntactic information similarly to monolinguals (L1), and what factors lead to a native-like processing. According to the Shallow Structure Hypothesis
Marinis, Theo +2 more
core +1 more source
One-week vaginal brachytherapy schedule as exclusive adjuvant post-operative treatment in intermediate- and high-intermediate-risk endometrial cancer patients [PDF]
Purpose: The aim of the study was to report survival outcomes and toxicities incidence by using one-week vaginal brachytherapy (VBT) schedule in intermediate- and high-intermediate-risk endometrial cancer patients.Material and methods: One hundred and ...
Giovanni Gravina +31 more
core +1 more source
En este artículo se somete a revisión la problemática cultural y temporal de la prehistoria tardía del desierto de Atacama de acuerdo a un estudio sistemático y comparativo de la alfarería funeraria de las dos cuencas, San Pedro y el Loa, que componen ...
Mauricio Iván Uribe Rodríguez
doaj +10 more sources
Background: Transcatheter aortic valve replacement–associated infective endocarditis (TAVR-IE) is a relatively rare complication of TAVR. Little is known about the characteristics of early, intermediate, and late-onset TAVR-IE.
Simrat Kaur, MD +13 more
doaj +1 more source

