Results 31 to 40 of about 340,011 (295)

Oromandibular Dyskinesia as the Initial Manifestation of Late-Onset Huntington Disease [PDF]

Journal of Movement Disorders, 2011
Huntington’s disease (HD) is a neurodegenerative disorder characterized by a triad of choreoathetosis, dementia and dominant inheritance. The cause of HD is an expansion of CAG trinucleotide repeats in the HD gene.
Dong-Seok Oh, Eun-Seon Park, Seong-Min Choi, Byeong-Chae Kim, Myeong-Kyu Kim, Ki-Hyun Cho   +5 more
doaj   +1 more source

The star formation history of intermediate-redshift late-type galaxies [PDF]

Monthly Notices of the Royal Astronomical Society, 2004
We combine the latest observations of disk galaxy photometry and rotation curves at moderate redshift from the FORS Deep Field (FDF) with simple models of chemical enrichment. Our method describes the buildup of the stellar component through infall of gas and allows for gas and metal outflows.
Ferreras, Ignacio, Silk, Joseph, Böhm, Asmus, Ziegler, Bodo   +3 more
openaire   +4 more sources

Eastern Mediterranean surface water temperatures and d18O composition during deposition of sapropels in the late Quaternary [PDF]

, 2003
Water column stratification increased at climatic transitions from cold to warm periods during the lateQuaternary and led to anoxic conditions and sapropel formation in the deep eastern Mediterranean basins.
Struck, U., Erlenkeuser, H., Emeis, K.C., Rossignol-Strick, M., Howell, M. W., Emeis, K.-C., Oba, T., Kroon, Dirk, Schulz, H., Kroon, D., Mackensen, Andreas, Sakamoto, T., Emeis, K. C., Koizumi, I., Ishizuka, S., Mackensen, A., Howell, M.W.   +16 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Observing a late folding intermediate of Ubiquitin at atomic resolution by NMR [PDF]

Protein Science, 2016
AbstractThe study of intermediates in the protein folding pathway provides a wealth of information about the energy landscape. The intermediates also frequently initiate pathogenic fibril formations. While observing the intermediates is difficult due to their transient nature, extreme conditions can partially unfold the proteins and provide a glimpse ...
Parag Surana, Ranabir Das
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Evaluation of maize grain yield in drought-prone environment [PDF]

Journal of Agricultural Sciences (Belgrade), 2017
Multi-location trial data obtained between 2007 and 2014 involving open pollinated varieties (OPVs) and hybrid maize (Zea mays L.) were analysed using GGE (Genotype and Genotype x Environment) and AMMI (Additive Main Effect and Multiplicative ...
Takim Felix Ogar, Olaoye Gbedabo, Abayomi Yakeen Abiola, Olakojo Samuel, Isah Matthew, Bankole Folusho, Ishaq Mohammed, Abdulmaliq Sulaiman Yussuf   +7 more
doaj   +1 more source

Modeling the climate response to a massive methane release from gas hydrates [PDF]

, 2004
[1] The climate response to a massive release of methane from gas hydrates is simulated in two 2500-year-long numerical experiments performed with a three-dimensional, global coupled atmosphere-sea ice-ocean model of intermediate complexity.
Goosse, H., Fichefet, Thierry, Beets, C.J.; id_orcid, C. J. Beets, Renssen, H., H. Goosse, Kroon, Dirk, Fichefet, T., D. Kroon, Kroon, D., Beets, CJ, Goosse, Hugues, Beets, C. J., T. Fichefet, Kroon, D, Beets, C.J., H. Renssen   +16 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Age of Laying Hens Significantly Influences the Content of Nutritionally Vital Lipophilic Compounds in Eggs

Foods, 2020
This study aimed to comparatively analyze the carotenoids, tocopherols, fatty acids, and sterols (e.g., cholesterol) in the eggs of laying hens of early (24 weeks), intermediate (42 weeks), and late age (74 weeks), utilizing high-performance liquid ...
Eun-Young Ko, Ramesh Kumar Saini, Young-Soo Keum, Byoung-Ki An   +3 more
doaj   +1 more source