Results 81 to 90 of about 1,430,130 (362)

Optical Studies of Twenty Longer-Period Cataclysmic Binaries

, 2010
We obtained time-series radial velocity spectroscopy of twenty cataclysmic variable stars, with the aim of determining orbital periods P_orb. All of the stars reported here prove to have P_orb > 3.5 h.
Peters, Christopher S., Skinner, Julie N., Thorstensen, John R.   +2 more
core   +1 more source

Antarctic climate, Southern Ocean circulation patterns, and deep water formation during the Eocene [PDF]

, 2017
We assess early-to-middle Eocene seawater neodymium (Nd) isotope records from seven Southern Ocean deep-sea drill sites to evaluate the role of Southern Ocean circulation in long-term Cenozoic climate change.
Anagnostou, Arsouze, Askin, Barron, Bice, Bijl, Bijl, Bijl, Bohaty, Bohaty, Borrelli, Boyle, Bralower, Brass, Browning, Burton, Cande, Chavagnac, Claire E. Huck, Contreras, Cook, Corfield, Coxall, Cramer, Creech, Danelian, De Baar, DeConto, Douglas, Dunkley Jones, Ehrmann, Elderfield, Flierdt, Flierdt, Francis, Freslon, Galeotti, German, Gingele, Goldner, Goldstein, Hague, Hinsbergen, Hohbein, Hollis, Hollis, Hollis, Houben, Huber, Huber, Huber, Huber, Huber, Huck, Jacobsen, Jeandel, Jovane, Katz, Kennett, Kennett, Kent, Kent, Kominz, Lawver, Le Houedec, Lear, Ling, Ling, Littler, Liu, Lunt, MacLeod, Martin, Martin, Martin, Martin, McIntosh, Miller, Moiroud, Norris, O'Nions, Orsi, Ortiz, Otto-Bliesner, Pagani, Pagani, Pak, Pankhurst, Passchier, Passchier, Peirce, Pekar, Pierce, Pierce, Pin, Poulsen, Pross, Pucéat, Rickli, Roberts, Roberts, Robinson, Samantha J. Hammond, Scher, Scher, Scher, Scher, Scher, Scher, Scher, Sexton, Sexton, Shaw, Sijp, Sijp, Soudry, Steven M. Bohaty, Stichel, Stille, Tachikawa, Tanaka, Tauxe, Taylor, Thomas, Thomas, Thomas, Thomas, Tina van de Flierdt, Truswell, Uenzelmann-Neben, Vandenberghe, Via, Weis, Wright, Zachos, Zachos, Zachos, Zachos   +137 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

SN 2007od: A Type IIP SN with Circumstellar Interaction [PDF]

, 2010
SN 2007od exhibits characteristics that have rarely been seen in a Type IIP supernova (SN). Optical V band photometry reveals a very steep brightness decline between the plateau and nebular phases of ~4.5 mag, likely due to SN 2007od containing a low ...
B. E. K. Sugerman, B. Ercolano, Barbon, Blondin, Couderc, D. L. Welch, Dwek, Fox, Fransson, Geoffrey C. Clayton, Gerardy, Hanner, Immler, Immler, Immler, J. Clem, J. E. Andrews, J. Fabbri, J. P. Chatelain, J. S. Gallagher, Kasen, Kotak, Kozasa, Landolt, Leonard, Lucy, M. J. Barlow, M. Meixner, Meikle, Mikuz, Pooley, R. Wesson, Smith, Smith, Sollerman, Sugerman, Welch   +36 more
core   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

SN 2016hil-- a Type II supernova in the remote outskirts of an elliptical host and its origin [PDF]

, 2019
Type II supernovae (SNe) stem from the core collapse of massive ($>8\ M_{\odot}$) stars. Owing to their short lifespan, we expect a very low rate of such events in elliptical host galaxies, where the star-formation rate is low, and which mostly consist ...
Brink, Thomas G., de Jaeger, Thomas, Filippenko, Alexei V., Fremling, Christoffer, Gal-Yam, Avishay, Irani, Ido, Kasliwal, Mansi M., Lunnan, Ragnhild, Masci, Frank J., Neill, James Don, Nugent, Peter E., Rebbapragada, Umaa, Schulze, Steve, Sollerman, Jesper, Yang, Yi, Yaron, Ofer, Zheng, WeiKang   +16 more
core   +4 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Morpho-agronomic performance of vetch species and their accessions grown under nitosol and vertisol conditions in the central highlands of Ethiopia

Agriculture & Food Security, 2018
Background Vetch is one of the promising forage legumes to mitigate the existing critical feed shortage problem in the Ethiopian highlands. The study was conducted to describe the morphological and agronomical traits and to examine the performances of ...
Gezahagn Kebede
doaj   +1 more source

Mind your Ps and Qs: the Interrelation between Period (P) and Mass-ratio (Q) Distributions of Binary Stars

, 2017
We compile observations of early-type binaries identified via spectroscopy, eclipses, long-baseline interferometry, adaptive optics, common proper motion, etc.
Di Stefano, Rosanne, Moe, Maxwell
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source