Results 61 to 70 of about 899,905 (333)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Optical Studies of Twenty Longer-Period Cataclysmic Binaries

, 2010
We obtained time-series radial velocity spectroscopy of twenty cataclysmic variable stars, with the aim of determining orbital periods P_orb. All of the stars reported here prove to have P_orb > 3.5 h.
Peters, Christopher S., Skinner, Julie N., Thorstensen, John R.   +2 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Characteristics of rainfall and erosion under natural conditions of land use in semiarid regions

Revista Brasileira de Engenharia Agrícola e Ambiental, 2013
The characteristics of rainfall can provide important information for management and land use may also minimize the water erosion problems. This study was carried out to evaluate soil and water loss in erosion plots with different coverage, and the ...
Cleene A. de Lima, Helba A. de Q. Palácio, Eunice M. de Andrade, Julio C. N. dos Santos, Paulilo P. Brasil   +4 more
doaj   +1 more source

Mind your Ps and Qs: the Interrelation between Period (P) and Mass-ratio (Q) Distributions of Binary Stars

, 2017
We compile observations of early-type binaries identified via spectroscopy, eclipses, long-baseline interferometry, adaptive optics, common proper motion, etc.
Di Stefano, Rosanne, Moe, Maxwell
core   +1 more source

The stochastic background: scaling laws and time to detection for pulsar timing arrays [PDF]

, 2013
We derive scaling laws for the signal-to-noise ratio of the optimal cross-correlation statistic, and show that the large power-law increase of the signal-to-noise ratio as a function of the the observation time $T$ that is usually assumed holds only at ...
Ellis, Justin, Jenet, Fredrick, Romano, Joseph D., Siemens, Xavier   +3 more
core   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Intensity modulated radiotherapy (IMRT) or conformational radiotherapy (3D-CRT) with conventional fractionation for prostate cancer: Is there any clinical difference? [PDF]

International Brazilian Journal of Urology
Purpose: To compare the treatment outcomes of a cohort of prostate cancer patients treated with conventional schedule using IMRT or 3DRT technique.
Gustavo Viani, Ana Carolina Hamamura, Alexandre C. Faustino   +2 more
doaj   +2 more sources

Early recurrence during the blanking period and left atrial reverse remodeling after catheter ablation for non-paroxysmal atrial fibrillation

International Journal of Cardiology: Heart & Vasculature, 2020
Background: Early recurrence of atrial tachyarrhythmia (ERAT) during a 90-day blanking period (BP) often occurs after atrial fibrillation (AF) ablation. Left atrial reverse remodeling (LARR), which is the reduction in LA volume (LAV), also occurs during ...
Takafumi Oka, Yasushi Koyama, Koji Tanaka, Yuko Hirao, Nobuaki Tanaka, Masato Okada, Issei Yoshimoto, Ryo Kitagaki, Atsunori Okamura, Katsuomi Iwakura, Yasushi Sakata, Kenshi Fujii, Koichi Inoue   +12 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source