Results 111 to 120 of about 1,127,406 (357)

War and Piety in the Grand Duchy of Lithuania in the Late Middle Ages

, 2017
S.C. Rowell
openalex   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

An Analysis of Contemporary Sources to Uncover the Medieval Identity of the Drink Bochet

EXARC Journal, 2020
When Le Ménagier de Paris (1393), a medieval household manual detailing a woman's proper behavior in marriage and running a household, was newly translated and republished as The Good Wife’s Guide: a Medieval Household Book by the Cornell University ...
Susan Verberg
doaj  

Depressive Symptoms in Middle Age and the Development of Later‐Life Functional Limitations: The Long‐Term Effect of Depressive Symptoms

, 2010
Kenneth E. Covinsky, Kristine Yaffe, Karla Lindquist, Elena Cherkasova, Edward H. Yelin, Dan G. Blazer   +5 more
openalex   +2 more sources

Cumulative Frailty in Late‐Middle Aged Men is Associated with Later Regional Abnormal White Matter and Decreased Processing Speed [PDF]

, 2023
Jack F.V. Hunt, Christine Fennema‐Notestine, Erik Buchholz, Michael J. Lyons, William S. Kremen, Carol E. Franz   +5 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The arms and armour of the municipal war wagon escort in 1521

Fasciculi Archaeologiae Historicae, 2000
...
Jan Szymczak
doaj  

METALLIC ARCHITECTURE OF CHINA IN LATE MIDDLE AGES: TYPOLOGY AND ARTISTRY

, 2020
Ren Nianchen
openalex   +1 more source

“Episcopus Nitriensis solvit pro complemento sui communis servicii.” Obligation of commune servitium of the bishops of Nitra towards the Roman Curia in the late Middle Ages. [PDF]

, 2023
Vladimír Rábik
openalex   +1 more source