Results 121 to 130 of about 2,125,321 (405)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Allevamento, transumanza, lanificio: tracce dall'alto e dal pieno Medioevo veneto [PDF]

open access: yes, 2012
All the research on the Venetoâs medieval sheep farm are based on few evidences, provided mostly by written documentation (available just for the Veronese territory).
Demo, E., Varanini, G.M.
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The helm of the kettle-hat type discovered at the motte in Leśno, Brusy commune, Bydgoszcz province

open access: yesFasciculi Archaeologiae Historicae, 1997
...
Marian Głosek, Krzysztof Walenta
doaj  

Luque en la Baja Edad Media [PDF]

open access: yes
A study of the Late Middle Ages in Luque, a feudal village located on the frontier with the Kingdom of Granada.Estudio sobre el pasado bajomedieval de Luque, una villa señorial emplazada en la Frontera con el Reino de ...
Pino García, José Luis del
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Vertèbres d’un ange de mer

open access: yesArchéopages, 2023
Stéphane Augry
doaj   +1 more source

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