Results 121 to 130 of about 123,973 (264)

Adolescent residential mobility, local nasal inflammation, and adult susceptibility to the common cold. [PDF]

Brain Behav Immun Health
Jang YS, Chiang J.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

U-Pb dating of volcaniclastic deposits from the Sinj Basin: implications for provenance and the tectono-sedimentary evolution of the External Dinarides. [PDF]

Int J Earth Sci
Šamarija R, Andrić-Tomašević N, Mandic O, Zeh A, Mužek K, Pavelić D, Schwotzer M.   +6 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Effects of Social Media on Adolescent Mental Health: Findings From a Population-Based Cohort Study in Australia. [PDF]

Med J Aust
Vijayakumar N, Dashti SG, Canterford L, Ellul S, Parissi AJA, Goddings AL, Viner RM, Moran P, Borschmann R, Mundy LK, Robson EM, Sawyer SM.   +11 more
europepmc   +1 more source

Religiousness in the Late Middle Ages [PDF]

, 2019
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

High precision CA-ID-TIMS U-Pb zircon age for the "Dueling Dinosaurs" locality, with implications for regional correlation, basal age and duration of the Hell Creek Formation, Montana. [PDF]

PLoS One
Roberts EM, Hendrix MS, Ramezani J, Clyde WC, Zippi P, Hodgson S, Yuleridge V, Zanno LE.   +7 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Dietary inequality marker reveals 10,000 years of gender and cultural disparity in Europe. [PDF]

PNAS Nexus
Colleter R, Jaouen K, Garcia D, Richards MP.   +3 more
europepmc   +1 more source