Genetic modelling of the weekly weight of Japanese quails using orthogonal Legendre polynomials. [PDF]
Üçtepe A, Kominakis A.
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Developmental trajectories of sleep in offspring of parents with mood disorders. [PDF]
Hubshman Z +9 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Reframing the epidemiological transition as increasing returns to tackling aging-related diseases. [PDF]
Ashwin J +4 more
europepmc +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
La vaisselle en terre cuite utilisée au xive s. à l’hôpital Saint-Julien de Chartres (Eure-et-Loir)
Grasping 14th century Chartres pottery was made possible thanks to the excavations of a latrine collection pit at Saint-Julien hospital, an institution for the blind founded in 1291 on a plot of land on the outer periphery of the town, in Faubourg Saint ...
Magali Gary
doaj
Tectono-paleogeographic evolution of the Northern Margin of the North China Block based on provenance analysis of Jurassic strata in Liaodong Peninsula. [PDF]
Xu J, Gao B, Pu C.
europepmc +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source

