Results 151 to 160 of about 2,125,321 (405)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The arms and armour of the municipal war wagon escort in 1521
Fasciculi Archaeologiae Historicae, 2000 ...
Jan Szymczak
doaj
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Toter Buchstabe - lebendiger Geist. Bibelauslegung als Lektüreereignis [PDF]
, 2017 There is scarcely a sentence in the New Testament that could have unleashed a wider reception history than Paul‘s comparison of the letter and the spirit in the third chapter of the Second Epistle to the Corinthians: "For the letter killeth, but the ...
Prica, Aleksandra
core
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Der Bote ist nicht allein: Historisch-anthropologische Überlegungen zu einer Reflexionsfigur der Medientheorie [PDF]
, 2017 Through their function as ‘figures of the third', messengers have taken on a special position in reflections on media and mediality. At the same time, this process has led to the messenger's de-historicization.
Schürch, Isabelle
core
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
EXARC at the Times and Epochs Festival, Kolomenskoye Park, Moscow
EXARC Journal, 2013 As an EXARC Board member, I attended the Times and Epochs Festival in Moscow from June 21-23, 2013 in the open-air museum Kolomenskoye Park. This year, an estimated 200,000 people attended the medieval themed festival where they were able to witness and ...
Bill Schindler
doaj
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source