Results 111 to 120 of about 4,144,511 (302)

History Matters at Ty Mawr Medieval Hall

EXARC Journal, 2014
Ty Mawr - ‘Great House’ Nestled in the hills of Montgomeryshire lies a gem of medieval history, the enigmatic Ty Mawr hall (Ball 2009a) rediscovered in the late 20th century, yet over 500 years old.
Gary Ball
doaj  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Cyprus between Late Antiquity and the Early Middle Ages (ca. 600-800)

, 2017
Luca Zavagno, Cyprus between Late Antiquity and the Early Middle Ages (ca. 600-800): An Island in Transition (Abingdon, Oxon: Routledge, an imprint of the Taylor & Francis Group, 2017)
Zavagno, Luca
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Vertèbres d’un ange de mer

Archéopages, 2023
Stéphane Augry
doaj   +1 more source

The Middle and the Late Bronze Age [PDF]

, 2018
The Middle and the Late Bronze ...
openaire  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Interpreting Transformations of People and Landscapes in Late Antiquity and the Early Middle Ages. Archaeological Approaches and Issues

, 2018
In this volume of papers, deriving from two conferences held in Rome and Leicester in 2016, nineteen leading European archaeologists discuss and interpret the complex evolution of landscapes – both urban and rural – across Late Antiquity and the Early ...
Seaman, Andy, Brogiolo, Gian Pietro, Meneghini, Roberto, Vigil-Escalera Guirado, Alfonso, Chavarría Arnau, Alexandra, Raynaud, Claude, Esmonde Cleary, Simon, Collins, Rob, Diarte-Blasco, Pilar, Heeren, Stijn, Arce, Javier, Christie, Neil, Goffredo, Roberto, Ariño, Enrique, Tompkins, Abigail E. I., Olmo Enciso, Lauro, Volpe, Giuliano, Rippon, Stephen, White, Roger   +18 more
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Byrne, Queenship in England, 1308-1485: Gender and Power in the Late Middle Ages (MadeGlobal Publishing, 2016)

, 2018
Review of Conor Byrne, Queenship in England, 1308-1485: Gender and Power in the Late Middle Ages (Almería: MadeGlobal Publishing, 2016)
Samuel Lane
core   +1 more source