Results 61 to 70 of about 3,970,472 (293)
A pan-European art trade in the late middle ages: Isotopic evidence on the master of Rimini enigma. [PDF]
Kloppmann W +5 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Serbian family in the late Middle ages
Marriage in Serbia in the middle ages was conducted only between persons belonging to the same social class. It was arranged and the woman would bring a dowry which would be controlled by the husband as long as the marriage lasted.
Siniša Mišić
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Mysteriously Liquefying Blood Relics in Italy
The properties of three Italian medieval religious blood relics, that periodically 'miraculously' liquefy, are described and two natural explanations proposed: they may either consist of a thixotropic substance, that can change from solid to liquid when ...
Luigi Garlaschelli, Giacomo Torzo
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
For the first time, this volume presents a geographically and phenomenologically broad range of case studies on late medieval changes of rule, from dynastic succession to conquest by force.
core +1 more source
Ages on weathered Plio-Pleistocene tephra sequences, western North Island, New Zealand [PDF]
Using the zircon fission-track method, we have obtained five ages on members of two strongly-weathered silicic, Pliocene-Pleistocene tephra sequences, the Kauroa and Hamilton Ash formations, in western North Island, New Zealand.
Liddell, Ivan J. +5 more
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source

