Results 81 to 90 of about 4,144,511 (302)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Krakow parish clergy at the end of the Middle Ages
, 1994 The article discusses the subject of Krakow clergy in the late Middle ...
Bolesław Przybyszewski
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Mapping Global Middle Ages, Toward a Global Middle Ages
, 2019 In Order to understand what a "global Middle Ages" might be, we need to define "global" in and in relation to the "Middle Ages." To do so, I turn to medieval (Christian) maps.
Asa Simon Mittman, Bryan C. Keene
core +1 more source
Time Management at School from the Late Middle Ages to the Industrial Age. A Few Cases in Point
, 2020 The aim of this essay is to account for the progressive development of strategies forvparcelling and organizing time at school, that is, the distribution and realization of tasks on a shared timeline.
Pruneri, Fabio
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Douze années d’études mudéjares (2001-2013)
Hamsa, 2014 The paper presents an overview on the mudéjar studies of the Iberian Peninsula in the late Middle Ages, from 2001 to 2013. The bibliographical profusion in the time considered, which brings together experts from different backgrounds, is displayed in a ...
Jean-Pierre Molénat
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Watch Elisheva Baumgarten's talk "Contending with Domestic Crises: Jewish Marriages in the Late Middle Ages" at Fordham University.
Andreas Lehnertz
core +1 more source