Results 191 to 200 of about 4,945,424 (246)

Fluorite material sources and magmatic-tectonic controls in hydrothermal fluorite deposits. [PDF]

PLoS One
Sun F, Qu C, Du X, Zhao X, Dong Y, Cao G, Zhou X, Ma X.   +7 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Recent explosive lava-water interaction in Tharsis, Mars. [PDF]

npj Space Explor
Pieterek B, Jones TJ.
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Associations between TMEM106B C-terminal fragment aggregation, age, and TDP-43 or tau pathology. [PDF]

Brain Pathol
Acewicz A, Tarka S, Grzegorczyk M, Rzepliński R, Wierzba-Bobrowicz T, Stępień T.   +5 more
europepmc   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

The Herbarium of Paolo Boccone from the Years 1689-1695 Kept in Wrocław (Poland): Plant Nomenclature, Taxonomy and Biogeography. [PDF]

Plants (Basel)
Drobnik J, Stebel A, Grenda-Kurmanow M, Alziar G.   +3 more
europepmc   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Impact of Pregnancy and the Postpartum Period on Sudden Sensorineural Hearing Loss and Other Audiological Changes. [PDF]

J Clin Med
Tomala N, Fecica P, Ciećka A, Graca J, Dudek G, Tracz A, Domaradzka N, Kluba D, Dorobisz K, Pazdro-Zastawny K.   +9 more
europepmc   +1 more source